Synopsis

Multicontrast, multiparametric and multidimensional MRI is a group of emerging paradigm-shifting MRI techniques that provides unique advantages over conventional MRI method in imaging speed and motion-robustness. It also offers a powerful platform for quantitative imaging and opens new opportunities for probing various physiological dynamics. In this talk I will provide an overview of the state of the art of vascular imaging based on multicontrast, multiparametric and multidimensional MRI, as well as an outlook for future research directions and clinical translation.

Target audience

Learning objectives

• Identify the main approaches including “traditional” methods, compressed sensing methods, and low-rank tensor methods;
• Define the main advantages of multiparametric and multidimensional MRI over conventional MRI for vascular imaging;
• Understand the current status of multiparametric and multidimensional MRI, and the unique opportunity and limitations it faces for clinical translation.

Acknowledgements

• NHLBI R01 HL096119
• NCI R01 CA217098
• Siemens Research Grants
• SCMR Seed Grant
• CSMC Precision Medicine Grant

References

• Saba, L., et al. AJNR 39.2 (2018): E9-E31.
• Wang, Jinnan, et al. MRM 69.2 (2013): 337-345.
• Fan, Zhaoyang, et al. JCMR 16.1 (2014): 1-12.
• Xie, Yibin, et al. JACC: CVI 10.6 (2017): 637-648.
• Hays A., Weiss R.G., Stuber M. (2012). Magnetic Resonance Angiography. Springer, New York, NY.
• Pang, Jianing, et al. MRM 72.5 (2014): 1208-1217.
• Coppo, Simone, et al. MRM 74.5 (2015): 1306-1316.
• Feng, L. I., et al. MRM 79.2 (2018): 826-838.
• Correia, Teresa, et al. MRM 80.6 (2018): 2618-2629.
• Bustin, Aurélien, et al. MRM 81.1 (2019): 102-115.
• Saam, T., et al. ATVB 25.1 (2005): 234-239.
• Coolen, Bram F., et al. MRM 75.3 (2016): 1008-1017.
• Qi, Haikun, et al. MRM 80.6 (2018): 2598-2608.
• Christodoulou, et al, Nat Biomed Eng. (2018).
• Wang, Nan, et al. MRM 81.4 (2019): 2302-2314.
• Ma, Liliana, et al. MRM 85.6 (2021): 3125-3139.