MRI is a powerful but inherently slow imaging technique. Methods of scan acceleration such as compressed sensing or simultaneous multi-slice imaging have significant benefits for both clinical research and diagnostic radiology but the way in which accelerated imaging can be validated and exploited varies between the two activities. This talk concentrates on acceleration by compressed sensing and asks the questions: for a specific measurement in clinical research, how do we define the acceptable degree of acceleration that should be used? And how does this differ if we are performing diagnostic imaging?
Collaborators: Volker Straub, Roy Taylor, Tim Cheetham, Pete Thelwall, Michelle McCallum, Sophie Cassidy, Anna Coombs.
David Higgins, Senior Clinical Scientist, Philips Healthcare, UK
Fellows : Claire Wood, Carl Peters, Ken Hodson, Mary Neal, Ben Pippard,
Students : Tom Loughran, Louise Mann, Lingzi Niu, Goy Shoowit, Will Hutton, Abi Silcock
Funding : Medical Research Council, Duchenne UK, Diabetes UK.
Review:
(1) Hollingsworth KG. Physics in Medicine and Biology 2015;60(21):R297-322.
CS Muscle :
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Loughran T et al., Radiology 2015; 275(2): 570-8.
Wood CL et al., European Journal of Endocrinology 2021; 184(1):67-79.
CS Liver/Abdomen :
Mann LW et al., Radiology 2016; 278(1): 247-56.
CS Lung 19F :
Neal MA et al., Magnetic Resonance in Medicine 2019; 82(4): 1301-1311.
Liver/pancreas steatosis and very low carlorie diets in T2D :
Al-Mrabeh A et al., Lancet Diabetes Endocrinol. 2020; 8 :939
Taylor R et al., Cell Metab. 2018; 28: 547