This talk will review the pathology of open spinal dysraphism and Chiari II malformation, the current surgical techniques for repair and the imaging criteria for fetal surgery. Relevant imaging findings on fetal and postnatal MRI in this population will be reviewed.
–Beth Kline-Fath, MD –Chief
–Kristina Stenger, RDMS
1. Nagaraj, U.D., Kline-Fath, B.M. Imaging of open spinal dysraphisms in the era of prenatal surgery. Pediatr Radiol 50, 1988–1998 (2020). https://doi.org/10.1007/s00247-020-04734-w
2. McLone DG, Knepper PA. The cause of Chiari II malformation: a unified theory. Pediatric Neuroscience. 1989; 15(1): 1-12.
3. Adzick NS, Thom EA, Spong CY, et al. A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med 2011; 364:993–1004.
4. Sutton LN, Adzick NS, Bilaniuk LT, et al. Improvement in hindbrain herniation demonstrated by serial fetal magnetic resonance imaging following fetal surgery for myelomeningocele. N Engl J Med 1999; 282(19):1826-31.
5. Didier RA, Martin-Saavedra JS, Oliver ER, et al. Fetal Intraventricular Hemorrhage in Open Neural Tube Defects: Prenatal Imaging Evaluation and Perinatal Outcomes. Am J Neuroradiol 2020; 41:1923-29.