Thomas O'Reilly1, Danny de Gans2, Lars Leenheer2, and Andrew Webb1
1C.J. Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Netherlands, 2DEMO, Delft University of Technology, Delft, Netherlands
Synopsis
Low field MRI has gained interest in recent years as a way of providing MRI to under-served and remote settings. MR hardware designed for such applications should be robust, portable and easy to maintain. In this work we present the design of a three-axis gradient amplifier capable of an output current of up to 15 amperes. The gradient amplifier is designed to run off two car batteries and consumes less than 100 watts during imaging. The components in the gradient amplifier are designed to be easily repairable and commonly available.
Introduction
There is increasing
interest in the capabilities of low-field MRI, with systems varying in field
strength from 0.55 T (1,2) to 50-200 mT (permanent
magnet arrays)(3-6) and 0.01T (large
homogeneous electromagnets). Permanent magnet systems in the 50-200 mT range
have been designed specifically for applications which require portability,
with systems ranging in weight from 75 kg (6) to ~500 kg (8,9). As part of making such
systems sustainable, the associated electronics such as RF and gradient
amplifiers should be as robust as possible with respect to operating
conditions, be easily repairable, and ideally be able to run of battery power
for operation in remote regions. Recently we described a three-axis current-output
gradient amplifier that was used to acquire three-dimensional images on a 50 mT
Halbach permanent magnet array (5). In this abstract we describe an improved version of this gradient
amplifier which makes it more robust and sustainable.Methods
The system operating at 50
mT (2.15 MHz) has been described in detail previously (6) and has gradients coils with inductances of 180, 225, and 225
mH
and resistances of 0.39, 0.41 and 0.42 ohms, respectively. The gradient
amplifier is driven by digital-to-analogue (DAC) gradient output boards from a Magritek
Kea 2 console (Aachen, Germany), with a voltage range of +/- 10 volt at a 16-bit
resolution.
Design specifications for
the new amplifier were: maximum current to the load +/- 15 Amps, maximum duty
cycle 30% per channel, load inductance between 20 and 300 mH, rise time 50 ms which results in a
bandwidth of 7 kHz, overload protection, driving a coil with equivalent series
resistance 0.4 W and parasitic parallel capacitance between the gradient
coils estimated at 130 pF. The amplifier is designed to run off an external
power source with a supply voltage between +/- 10.5V and +/- 15V. To facilitate
the use of batteries, where the voltage drops as the battery discharges, the
biasing of the amplifier is made relative to the relevant power supply rails. When
the batteries are drained an under-voltage lock-out disables the amplifiers at
a threshold voltage of 10.5 volts. Two 20 Amp car fuses (ATO Blade) are used
for protection at the positive and negative terminals. Filters are placed on
the power supply lines to reduce noise introduced by the power supplies.
A four layer PCB
configuration was designed with each layer designed for a specific purpose: the
upper layer 1 had most of the components for easy access, replacement and
routing, layer 2 was a ground layer for thermal stability and optimal heat
spreading which is separated per channel to prevent cross coupling, layer 3
routes the power and layer 4 contains the high power components with wide
copper tracks. The constructed amplifier is shown in Figure 1.
An image of the lower leg
was acquired using the gradient amplifier to drive the gradient coils. The image
was acquired using a 3D TSE sequence with the following parameters: FoV: 150x150x200 mm,
resolution: 1x1x4 mm, TR/TE: 400 ms/8 ms, ETL: 10, acquisition bandwidth: 20 kHz.Results
Figure 2 shows a schematic
of one of the channels of the improved gradient amplifier (each channel is
identical). At a 3A average discharge current, which was typical for an imaging
session, the batteries lasted 5-6 hours.
At 2 MHz the measured voltage
noise on the output noise was -123 dBm/Hz, so roughly 50 dB above thermal noise.
Although an RF shield is in place between the gradient coils and the RF coil,
this does not provide sufficient attenuation without being extremely thick
which introduces significant eddy currents. Notch filters, see Figure 3(a,b),
were designed at the gradient amplifier outputs which gave over 40 dB
attenuation. Noise measurements performed at 2.15 MHz using an RF coil placed
at the center of the system showed no increase in the measured noise by the
spectrometer after the gradient amplifiers were switched on.
Figure 4 shows the step
response of one of the channels when driving an inductance of 213 mH with ESR of 0.32 W. The waveforms show high
fidelity at lower driving currents, whereas it is clearly seen that at 15A the output starts to limit the slew rate because of clipping
to the supply rail.
Figure 5 shows a single coronal slice of the lower leg reconstructed
from a 3D dataset.Discussion
We demonstrate a low-cost highly portable 3 channel gradient
amplifier designed for small MRI systems that is capable of running of two 12V
batteries. Power consumption during imaging is less than 100 Watts, low enough
to easily run off solar power. The PCB is designed to be easily repairable and
commonly available components are used wherever possible to improve
sustainability further. The gradient amplifier was tested on a small head sized
system where we were able to obtain gradient strengths of up to 10 mT/m and a
slew rate of 40 T/m/s. The slew rate of the gradient amplifier could be
improved by using higher voltage as shown in figure 4 but would require larger
power supplies and increased power consumption.Acknowledgements
This work is supported by the following
grants: Horizon 2020 ERC FET-OPEN 737180 Histo MRI, Horizon 2020 ERC Advanced
NOMA-MRI 670629, Simon Stevin Meester Award and NWO WOTRO Joint SDG Research
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