Yenal Gokpek1 and Ozkan Doganay1
1Institute of Health Sciences, Ege University, IZMIR, Turkey
Synopsis
In this study, the design and construction of a hybrid
Helmholtz coil system and numerical modelling were investigated for production
of homogeneous magnetic field over a volume of interest that consist of
cylindrical geometry (h=700mm, r=90mm). The 4‑coil system was constructed
and tested by two commercially available low power DC power supplies. The magnetic
field created by the 4‑coil system was found to be B=2.5182±0.0035mT over the
volume of interest. We found that the simulated and measured magnetic fields
are in good agreement (R=0.9759, p<0.05).
Introduction
The novel
hyperpolarized magnetic resonance imaging technologies does not required the
use of high‑field MR systems and the imaging can be performed with the low
magnetic field MR strengths in the order of 5mT 1–4. Creating a homogeneous low magnetic
field throughout a volume of interest (VOI) that includes the body parts to be
imaged is of great importance in terms of image quality and is very
challenging. Another important relevant application of the low magnetic field is
the spin exchange optical pumping (SEOP) technique that is used to polarize noble
hyperpolarized contrast agents including 1H, 3He, 7Li,
13C, 15N, 19F, 31P, 83Kr,
and 129Xe 5. In this study, a hybrid Helmholtz
coil configuration was simulated and designed providing a homogeneous magnetic
field and excellent efficiency for the use of SEOP system and/or low-field MR
imaging systems.Materials and Methods
Numerical
simulations: A hybrid
Helmholtz system geometry was simulated in MATLAB for optimizing magnetic field
homogeneity and field strength of coil system that consist of four coils as
shown in Figure 1. The magnetic field was computed by solving Biot‑Savart laws
using a fixed mesh size of 2mm. The 4‑coil system consisted of (i) two pairs
of larger coils (i.e. coils I and IV in Figure 1) with an inner‑diameter of 600mm
that are separated from center for 425mm which has a turn number of 140, (ii)
two smaller coils (i.e. coils II and III in Figure 1) with an inner‑diameter of 600mm that
are separated from center for 127mm which has a turn number of 80. Electric
current values were selected based on the maximum currents supplied by the DC
power sources (Marxlow KXN-3020D).
Design
and construction: A
total length of 860m copper wire with a diameter of 3mm were reel on aluminum cylinders
for building the coil pairs. Each coil pair was driven with two separate power
sources and fed with an electric current of approximately 10A for controlling the
magnetic field uniformity.
Measurement
of magnetic field: The
generated magnetic fields along the coil axis from point A to B and radii from
point C to D (Figure 1) are measured using a gaussmeter
(PCE‑MFM‑3000) with 10mm distances. The measured magnetic field compared to the
simulated magnetic field using Spearman’s correlation. The VOI is chosen to be
700mm long, 90mm wide and in the middle of the coil systems.Results
The 4‑coil hybrid
system produced a magnetic field up to 7mT when fed with an electric current of
20A. The cross‑section of simulated magnetic field is shown in Figure 2a.The simulated and measured line
profiles along the coil axis (from A to B in Figure 2a) are also shown in Figure 2b. The magnetic field variations were less than
3% within the VOI. The
experimental results measured along the coil radii are also compared with the
line profiles of the 4‑coil system that corresponds to the line profiles shown
in Figure 3. Correlation values between experimental
and simulated line profiles: A‑B, C‑D, E‑F, G‑H, and I‑J were 0.976, 0.988,
0.978, 0.982 and 0.988, respectively with p‑values are lower than 0.001.Discussion
Magnetic
field values and homogeneity over the VOI of designed system were suitable for
the purpose of use (SEOP and low field MRI) according to simulated and measured
results. The magnetic field homogeneity simulated with the 4‑coil system was
close enough to the system with quite large dimensions (2000mm) previously used
by another team 1, showing that the 4‑coil system was
suitable for a large region of interest with the advantage of smaller
dimensions. The experimental measurements showed that the simulated and
measured magnetic fields was statistically in agreement and homogeneity was acceptable
for the purpose of use and for a large VOI. Further improvements may include a
fifth coil driven with a separate power supply for fine shimming in between the
larger coils with varying turns.
The
difference of ~5% between experimental and theoretical values that may
originate from the sensitivity of the gaussmeter or the amplifying effect of
the coil spools/surrounding ferromagnetic materials, which is in agreement with
the similar results in literature showing the experimental magnetic field
measurements can be 0.02mT above the simulated magnetic field. While there are
more homogeneous magnetic field generating systems that include four circular
coils in the literature, such as Lee-Whiting et al.6, the VOI is usually much
shorter than our study for the same physical dimensions.Acknowledgements
This work was supported by the TUBITAK Project No 118C189.References
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