Afis Ajala1, Yihe Hua1, Desmond Teck Beng Yeo1, Mark Vermilyea1, and Thomas Foo1
1GE Global Research, Niskayuna, NY, United States
Synopsis
A unique approach to providing a more open, less claustrophobic
whole-body MRI is presented. A design for an asymmetric gradient coil moves the
region of interest (ROI) towards one end of the gradient coil, shortening the
gradient coil length from the isocenter to the patient opening. This results in
a stepped configuration where the patient-bore diameter outside of the imaging
ROI is substantially wider compared to using a conventional symmetric gradient
coil design. The stepped patient bore has previously been used in head-only
gradient systems where the greater openness has resulted in increased patient
comfort and reduced claustrophobia.
Introduction
Symmetric whole-body gradient coils (sWBG) are widely used in whole-body
magnetic resonance imaging (MRI) scanners. The long cylindrical geometry of
symmetric gradient coils limits the patient bore space, even at 70 cm. There is
still a significant incidence of claustrophobia or reports of patient
discomfort due to the constrained space1. One method for increasing the patient bore
size is to increase the size of the magnet warm bore, and the corresponding gradient
coil inner diameter. However, this comes at an increased magnet size and cost to
maintain, and also reduced gradient coil efficiency from the larger diameter
gradient coil2,3.Purpose
The goals of this work are: (1) Design
a transverse asymmetric whole-body gradient coil (aWBG) and compare the
performance to that of a symmetric design (sWBG). (2) The free-space electric
field ($$$\vec{E}$$$-field) of the aWBG coil is compared to that of the sWBG
coil as an assessment of peripheral nerve stimulation (PNS), as an indication of magneto-stimulation levels4.Materials and Methods
Design
of aWBG: The aWBG
design was carried out using custom tool written in MATLAB (Matworks,MA,USA). A finite element method with boundary
current sources was used to optimize the current density created by a two-dimensional
stream function. The actively shielded gradient coil was designed for a
gradient driver current and voltage specification of 900 A and 2000 V
respectively. An axially asymmetric
design was adopted for the transverse coils and a symmetric design was used for
the z coils. The bore diameter of the sWBG and aWBG coils outside the FOV at
the patient end are 960 mm and 753 mm respectively. The bore diameter inside
the FOV to the service end remains the same (753 mm) for the two coils (Figure
1). The length of the aWBG gradient coil from the isocenter to the patient end
is shorter (400 mm) compared to the sWBG design that is 780 mm long. More details of the sWBG and aWBG coils are summarized in Table
1.
Analyses: After normalizing
the gradient amplitude (Gmax) of the coils to 10 mT/m, the magnetic vector
potential field (A-field) and the corresponding magnetic field of the designed
gradients were calculated directly using the Biot-Savart Law in a 3D grid of 2 x 2 x 2 mm3 spatial resolution. The obtained A-field was used to calculate the E-field in free
space at 1 kHz (steady state sinusoid) for the y and z coils. Percent difference in the E-field magnitudes were
calculated relative to a rheobase of 6.2 V/m6.Results and Discussions
The inner
diameter of the sWBG and aWBG coils were measured in the imaging region, and
also outside of the imaging region at the patient end. These were 753 mm
diameter within the imaging region, and 890 mm outside of the aWBG coil at the
patient end (Figure 1). The gradient inner diameter in the imaging region to
the service end remained the same at 753
mm for the two coils. The length of the aWBG gradient coil from the isocenter
to the patient end was shorter (400 mm) compared to the sWBG design (780 mm). The 890 mm bore would be the largest for any
MRI system. The aWBG coil length from the isocenter to.the patient end was about
50% shorter compared to the sWBG coil. Data for the sWBG and aWBG coils are
summarized in Table 1The primary and shield coil turns of the aWBG and sWBG designs
are shown in 3D for the x, y and z gradient axes in Figure 2.
The $$$ |\vec{E}|$$$-field
magnitude as well as difference between the the sWBG and aWBG designs for the y
and z coils are shown in Figures 3-4. $$$\vec{E}$$$-field difference was high
as 14% between the sWBG and aWBG y-gradient coils in the coronal plane, and 9%
in the axial plane (Figure 3).
With the
lower inductance of the aWBG of 602 mH
compared to 817 mH
of the sWBG, the maximum gradient amplitude achieved with the aWBG design was 47
mT/m compared to 80 mT/m of the sWBG. This reduction in attainable $$$G_{max}$$$
on the aWBG coil can be attributed to
the lesser coil efficiency of the asymmetric coil design. The aWBG transverse
coil design delivered an $$$SR_{max}$$$ of 163 T/m/s and 155 T/m/s in the x and
y directions, respectively. The z-coil gave an $$$SR_{max}$$$ of 212 T/m/s. The aWBG coil has a lower $$$SR_{max}$$$
compared to the sWBG coil despite its
lower inductance because of its lower coil efficiency.
Lower $$$\vec{E}$$$-field
values were obtained for the aWBG coil compared to the sWBG around the head and
abdomen of the human overlay (Figures 3-4). The aWBG y-coil resulted higher $$$\vec{E}$$$-field
values (compared to the sWBG coil) on the service end and about comparable
values in the chest region. This increase in $$$\vec{E}$$$-field values may be
attributed to increased coil turn density of the aWBG coil, especially at the
service end of the coil. Conclusion
We have
analyzed the design and $$$\vec{E}$$$-fields of an asymmetric gradient coil for
a whole-body MR system to provide a more open stepped patient bore. The lower aWBG coil efficiency (compared to
sWBG) can be addressed by adopting a more powerful gradient driver.Acknowledgements
No acknowledgement found.References
[1] Y. Wang, F. Liu, Y. Li, F. Tang, and S.
Crozier, “Asymmetric gradient coil design for use in a short, open bore
magnetic resonance imaging scanner,” Journal of Magnetic Resonance, vol.
269, pp. 203–212, Aug. 2016, doi: 10.1016/j.jmr.2016.06.015.
[2] D.
Tomasi, R. F. Xavier, B. Foerster, H. Panepucci, A. Tannús, and E. L. Vidoto,
“Asymmetrical gradient coil for head imaging,” Magnetic Resonance in
Medicine, vol. 48, no. 4, pp. 707–714, 2002, doi: 10.1002/mrm.10263.
[3] T. K.
F. Foo et al., “Highly efficient head-only magnetic field insert
gradient coil for achieving simultaneous high gradient amplitude and slew rate
at 3.0T (MAGNUS) for brain microstructure imaging,” Magnetic Resonance in
Medicine, vol. 83, no. 6, pp. 2356–2369, 2020, doi: 10.1002/mrm.28087.
[4] M.
Bencsik, R. Bowtell, and R. M. Bowley, “Using the vector potential in
evaluating the likelihood of peripheral nerve stimulation due to switched
magnetic field gradients,” Magnetic Resonance in Medicine, vol. 50, no.
2, pp. 405–410, 2003, doi: 10.1002/mrm.10520.
[5] C.
Niu et al., “Numerical Design of High-Efficiency Whole-Body Gradient
Coils With a Hybrid Cylindrical-Planar Structure,” IEEE Transactions on
Biomedical Engineering, vol. 66, no. 6, pp. 1628–1636, Jun. 2019, doi:
10.1109/TBME.2018.2877429.
[6] W.
Irnich and F. X. Hebrank, “Stimulation threshold comparison of time-varying
magnetic pulses with different waveforms,” Journal of Magnetic Resonance
Imaging, vol. 29, no. 1, pp. 229–236, 2009, doi: 10.1002/jmri.21573.