Yuqing Wan1, Nathan Ooms2, Paul Nguyen1, and Guangqiang (Jay) Jiang1
1Axonics Modulation Technologies, Irvine, CA, United States, 2Purdue University, West Lafayette, IN, United States
Synopsis
This study reported magnetic resonance imaging (MRI) examination
duration of 974 patients collected from two imaging sites. Statistical scan
time analysis was performed, and distributions were obtained for different scan
regions. Scan time disparities were found between the two imaging sites due to
the sequence selections and configuration, which may impact imaging cost and
image quality. The clinical examination duration data provides useful
information for implant device manufacturers to define practical MRI conditions that improve the
patients’ overall MR experience.
Purpose
This study collected 1.5T MR patient scan times from 2
clinical imaging sites and performs statistical analysis on the scan time for various
body regions. Scan time distributions for different scan regions are compared
between the imaging sites, providing practical insight about the expected scan
time range for patients. This also provided useful scan time information for
implant device manufacturers to develop MRI labeling suited for clinically
relevant MR sessions.Methods
Examination duration data from a total of 974 patients were
collected from 2 clinical imaging sites over the course of 2 years. For site A,
data were obtained from 484 patients on a GE 1.5T scanner (Optima 450W), and
for Site B, data were obtained from 490 patients on a Siemens 1.5T scanner (Avanto
Fit/Aera). The scan regions analyzed in this study include Head/Brain, Lumbar
Spine, Abdomen, Cardiac, Prostate and Breast. All the scans were performed in
Normal Operating Mode with maximum whole body SAR of 2W/kg and maximum head SAR
of 3.2W/kg. The examination duration was determined from image timestamps
logged on the scanners for each patient. Statistical analysis is performed on
the examination duration for each scan region, and histogram plots are
generated to show the distributions.Results
Table 2 shows the mean and standard deviation for the
examination duration for each scan region and imaging site, as well as sites
combined.
The histogram of the examination duration for each scan
region is shown in Figure 1 for Site A, Site B and Site A and B combined. Discussion
In this study we presented examination duration statistics
under Normal Operating Mode for patients undergoing 1.5T clinical MR scans. For
the frequent scan regions covered in this study, the average examination
duration ranges from 17.9 to 69.6 minutes. There is a disparity in patient
examination duration for the same scan region (up to 48 % difference in Breast
scan) from the two imaging sites. Imaging centers differ in sequence selection
for their protocols. These variations are typically determined by the
Radiologist or Radiology Group overseeing the imaging site. Most exams have
similar sequences for the body part being imaged, but certain sequences chosen
by the Radiologist can significantly alter the total exam duration, SAR, and
B1+rms. There can also be differences in the parameters of these sequences
between imaging sites. For example, Site A uses a 2D Sagittal T1 FLAIR and 2D
Axial T1 FLAIR as the standard T1 sequence in the brain, whereas Site B uses a
Sagittal T1 3D MPRAGE with reformats (Table 3). FLAIR imaging uses
significantly higher B1+rms and SAR as compared to the MPRAGE sequence. The
distinct protocols from imaging sites may also lead to differences in image
quality.
The examination duration analyzed in this study includes
continuous scanning time and interscan time. Head/Brain, Lumbar Spine,
Prostate, and Breast imaging utilize minimal/negligible interscan time with
interscan time consisting of less than 5% of the overall examination duration.
Therefore, these scans can be considered as continuous scanning examinations. Abdominal
and Cardiac Imaging utilize repeated and lengthier interscan times. Breath
holding instructions constitute marked times in between sequences.
The examination duration for various body parts provides relevant
information for implant device manufacturers while assessing time-dependent heating
hazard from the exposure to RF and switching gradient fields. As a result, many
device manufacturers specify a maximum allowed active scan time before a wait
time is needed1 or within a scanning window2. This additional wait time
requirement could drastically change the overall MR session time for prostate scans
(100% exceeding 30 minutes) and cardiac imaging (100% exceeding 30 minutes with
71% over 60 minutes). Furthermore, implant device manufacturers may also specify
a more restricted RF exposure limit (SAR or B1+rms) which further extends the
scan time. The detailed analysis on the relationship of wbSAR limit and scan
time can be found in 3. Conclusion
This study reported patient MR examination duration from two
imaging sites. The data demonstrated scan duration disparities between two imaging
sites even for the same scan regions. This may impact imaging cost as well as
diagnostic image quality. Implant device manufacturers may utilize this
information for developing MRI labeling that offers the patient the best possible
MR experience. Acknowledgements
No acknowledgement found.References
1.
MRI Guidelines, Axonics Sacral Neuromodulation
System, 110-0092-001rM.
https://www.axonics.com/hcp/resources/resource-library
2.
MRI
Guidelines for InterStim systems
97810 3058 3023, 2020-07-15.
http://manuals.medtronic.com/content/dam/emanuals/neuro/M980291A_a_015_view_color.pdf
3.
Y Wan et al, Impact of 1.5T SAR Limits on the MRI Scan Time for
Implantable Devices, ISMRM 2021