Synopsis

This lecture is to provide fundamental principles of dynamics contrast enhanced (DCE) magnetic resonance imaging (MRI) from the perspective of acquisition. We will talk about T1-weighted dynamic data acquisition for DCE MRI, dynamic T1 (t) quantification with correction of B1 field inhomogeneities, and conversion of T1 maps to concentrations. We move on to delineation of contrast dynamics with time and discuss why we need to have high spatial and temporal resolution for accurate quantification of perfusion and microvascular permeability. Then, I will introduce some of the state-of-the-art, high resolution DCE MRI methods.