Synopsis

Extracellular agents are distributed within the extracellular interstitial space. Gadolinium chelates, which are formed by the chelation of gadolinium to organic ligands such as diethylenetriaminepentaacetic acid, constitute a class of extra-cellular agents. Although several formulations are available with different ligands, their pharmacologic characteristics and imaging considerations are essentially identical. There are multiple indications for the use of extracellular contrast agents in MR imaging of the liver. These include lesion detection, lesion characterization, and liver vasculature assessment. In this lecture, I will talk about “representative pearls and pitfalls” of the GD-EOB-DTPA Liver MRI, comparing ECA enhanced liver MRI.