Synopsis

Diffusion imaging can non-invasively probe tissue microstructures and has been widely adopted in clinical diagnosis and neuroscience research. In this section, we will briefly review the diffusion imaging contrast mechanisms and discuss the workhorse diffusion imaging sequence, which is single-shot spin-echo EPI. We will also discuss some recent diffusion imaging techniques such as multi-shot diffusion imaging, simultaneous multi-slice imaging, 3D imaging, etc. This section aims to give a comprehensive overview on diffusion imaging physics.