Tino Ebbers1
1Linköping University, Sweden
Synopsis
Blood flow
is crucial in the development, diagnosis and treatment of many cardiovascular
diseases. For many years, two-dimensional (2D), one-directional, time-resolved flow
MRI has been the technique of choice. Nowadays, fast 4D flow MRI sequences exist
on all modern MR systems and several commercial analysis software solutions are
available. The challenge is to selected the most promising and relevant parameters
for the research or clinical question at hand, and to obtain these with
sufficient quality in a short acquisition and analysis time.
Target audience
This lecture is targeted towards those
professionals interested in understanding, measuring, and improving the value
of cardiovascular flow imaging MRI. The targeted audience includes engineers,
basic scientists, and MD's who want to maximize the impact of their 4D flow MRI
research or to improve the clinical workflow of cardiovascular flow imaging.Educational Objectives
After the lecture, the attendees should be able
to
1.
Understand the basic principles of MRI flow measurements.
2.
Identify and minimize potential artifacts in MRI flow measurements
3. Optimize
the acquisition approach and data analysis of 2D flow MRI and 4D flow MRI
4. Understand
the advantages and disadvantages of 2D flow MRI and 4D flow MRIScope
Blood flow
is crucial in the development, diagnosis and treatment planning of many cardiovascular
diseases. Flow MRI is the most versatile, flexible and accurate technique to non-invasively
measure blood flow in the human body. For many years, time-resolved one-directional,
two-dimensional (2D) flow MRI has been the technique of choice. Nowadays, fast time-resolved
three-directional three-dimensional (4D) flow MRI sequences exist on all modern
MR systems and several commercial analysis software solutions are available,
which has made 4D flow MRI a part of many research and clinical MRI protocols. Clinically
acceptable scan times of 4D flow MRI can be obtained by combining several
advanced acceleration techniques. These accelerations techniques of 4D flow MRI
do all, to a small or large extend affect, affect data quality. The optimal
choice of acceleration techniques depends on the available scan time and the
application at hand. But also the choice of analysis parameter can be challenging.
A wide range of local, regional and global parameters have been proposed and
have been used in research studies, while some of them also are in used clinical
practice. The challenge is to selected the most promising and relevant parameters
for the research or clinical question at hand, and to obtain these with
sufficient quality in a short acquisition and analysis time.Acknowledgements
No acknowledgement found.References
No reference found.