Erik H Middlebrooks1
1Mayo Clinic, Jacksonville, FL, United States
Synopsis
Recent advances in electrophysiological and neuroimaging techniques have refined our understanding of basal ganglia connectivity. These advances stand to improve our understanding of human disease, as well as further refine therapeutic techniques, such as deep brain stimulation. This presentation highlights current understanding of basal ganglia connectivity with an emphasis on common disease processes, as well as exploration of neuroimaging techniques for assessing basal ganglia.
TARGET AUDIENCE
Content of this presentation is targeted to those wishing to gain an understanding of basic anatomy of the basal ganglia, as well as updates on basal ganglia connectivity. The content also serves to present updates in basal ganglia imaging techniques.OUTCOME/OBJECTIVES
- Gain an understanding of the 3D anatomical relationships of the basal ganglia nuclei
- Understand basic basal ganglia connectivity and function, with an emphasis on common pathological disorders and therapeutic targets
- Learn common imaging techniques for assessing basal ganglia structure
PURPOSE
The first coherent models of basal ganglia function and circuitry were devised in the mid-1980s. Although revolutionary in our understanding, these models continue to be refined today. New electrophysiologic and imaging tools have allowed an unprecedented advancement in the understanding of basal ganglia function. This advancement in knowledge has provided insights into the pathological basis for many neurological disorders. Additionally, they have allowed improved understanding of the mechanism of action and improved targeting for related therapies, such as deep brain stimulation. Advancements in neuroimaging, such as ultra-high field MRI, diffusion tensor imaging, and morphometric analysis, will be used to review and highlight key basal ganglia anatomy and function.Acknowledgements
No acknowledgement found.References
No reference found.