Kyoko Fujimoto1, Tayeb A Zaidi1, David Lampman2, Joshua W Guag1, Hideta Habara3, and Sunder S Rajan1
1Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD, United States, 2Hitach Healthcare Americas, Twinsburg, OH, United States, 3Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan
Synopsis
There is an
increasing use of open-bore vertical Magnetic Resonance (MR) systems which consist
of two planar radio-frequency (RF) coils. These planar coils generate different
electric field distributions compared to that of the conventional cylindrical coils.
A recent study showed that RF-induced heating of a neuromodulation device was
much lower in the open-bore system. However, imaging landmarks other than the
brain have not been evaluated. In this study, we examined the differences in RF
exposure using computational modeling and compared specific absorption rate in
an anatomical human model at a 1.2T open-bore system with a 1.5T conventional
system.
Introduction
There are two
common risks faced in the practice of non-contrast Magnetic Resonance Imaging
(MRI): adverse events such as skin burns and radio-frequency (RF) induced
thermal injury in patients with implantable medical devices. Both risks are due
to high electric field (E-field) exposure in tissue that is produced by the
body RF coil for a given B1+ field needed for imaging1.
The most
common body RF coil design used is a cylindrical birdcage resonator. There is an
increasing use of an open-bore vertical system which consists of two planar
coils. The E-field distribution generated by the open system is different from
that of the conventional cylindrical coil. A recent study showed that RF-induced
heating of a neuromodulation device was much lower in the open system2.
However, imaging landmarks other than the brain have not been evaluated. In
this study, we examined the differences in RF exposure using validated computational
modeling and compared specific absorption rate (SAR) in an anatomical human
model in a planar coil (49.6MHz) and a conventional birdcage coil (64MHz). Methods
Measurements for modeling validation
Fifteen data
points of E-field and magnetic field (H-field) were collected in the ASTM
phantom using a hand-held measurement system with an E-field probe and a
H-field probe (EASY4MRI, SPEAG, Switzerland) in a 1.5T high-pass birdcage body
coil (MITS1.5, Zurich Med Tech,
Switzerland) and a commercial open-bore 1.2T MRI system (OASIS, Hitachi,
Ltd., Japan). The data was acquired with
a 5×3 grid with 9.45cm and 9cm spacing in the coronal slice.
The probes were
calibrated to a specific pulse sequence which was not available at both
systems. To mitigate this, the difference factors were calculated based on
measurements using TEM Transmission cell (Model 8802, Narda, USA) for both
probes at 49.6MHz and 64MHz. The measurement results were scaled independently with
the difference factors.
Modeling
The
simulations were first performed with the ASTM phantom at 49.6MHz for the open
coil (Fig.1(a)) and at 64MHz for the conventional birdcage coil (Fig.1(b))
using the Sim4Life platform (V4.4, Zurich Med Tech, Switzerland). The ASTM
simulation results were scaled with B1+ = 2μT at the coil isocenter. Then
simulations with the AustinMan model3 were performed at the heart,
hip bone, and knee imaging landmarks for both coils. The coils were modeled
based on the physical coils used for the measurements (OASIS2,4 and MITS1.55). For
the open simulation, the Huygens’ Approach6 was used. The incident
field was calculated with an unloaded coil first, then used to compute fields
within the body model with 2mm isotropic grid. For the birdcage simulation, the AustinMan model was discretized with 2mm and the coil was discretized up to 0.98mm to include small components in the grid. The birdcage results were
resampled to 2mm isotropic grid. These grid differences are expected to have a
minor effect to our results as a previous study reported7. The SAR1g
results were normalized to whole-body SAR = 2W/kg. Results
Measurement
The scaled measurement
results were compared with the simulation results (Fig.2). The correlation (R2)
of the E-fields was 0.89 for the open coil and 0.99 for the birdcage coil. The
correlation of the H-fields was 0.85 for the open coil and 0.71 for the birdcage
coil.
Modeling
SAR1g
results calculated in the AustinMan model were compared for each imaging
landmark. The maximum SAR1g comparison showed that SAR1g in
the birdcage coil was higher than that in the open coil for all the imaging
landmarks (Fig.3(a)). The anatomical structures where the maximum SAR1g
were found were different for each coil as summarized in Fig.3(b). The
anatomical locations with the maximum SAR1g were identified in
coronal slices (Fig.4). The SAR1g results were further analyzed and
maximum values were calculated along the axial plane of the AustinMan body
(Fig.5). The maximum SAR1g anatomical
locations for heart, hipbone and knee were upper back, lower back and groin (for
the open coil), and arm, groin and knee (for the birdcage coil), respectively.Discussion
SAR1g
maps showed considerably different distributions between the two coils. This
was due to the differences in coil geometries as well as the locations of
sources. For the birdcage coil, side of the bodies (arm and knee) showed higher
SAR. For the open coil, body parts close to the bottom coil (upper and lower
backs) showed higher SAR. These results suggest that for patients with
implantable devices, a higher safety margin could be achieved if the scanner
was chosen based on the advantageous E-field/SAR distributions for each coil
type. For instance, there may be a lower risk of RF-induced heating in the open
system for patients with knee implants as shown in Fig.5. Current MR Conditional implantable devices are
limited to scanning on cylindrical systems. This study suggests that scanning
on open coil systems may offer improved RF safety margins for some devices and
expand patient access to MRI. Conclusion
The SAR1g results at the 1.2T
open-bore system and the 1.5T conventional system showed that RF exposure is
different at heart, hipbone and knee imaging landmarks. MR safety testing for
implants designed to include MR systems with different coil architectures could
provide improved patient access to MRI
scans. Acknowledgements
Disclaimer: The mention
of commercial products, their sources, or their use in connection with material
reported herein is not to be construed as either an actual or implied endorsement
of such products by the Department of Health and Human Services.References
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