Cardiac metabolic imaging using hyperpolarized [1-13C]lactate as a substrate

Author:Angus Lau  Albert Chen  Charles Cunningham  

Institution:Ge Healthcare  GE Healthcare  University of Toronto  Sunnybrook Research Institute  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4312  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 112  

Detecting early response to PD-L1 blockade by 13C MRI

Author:Yu Saida  Tomohiro Seki  Kazu Yamamoto  Jeffery Brender  James Mitchell  Murali Krishna  Shun Kishimoto  

Institution:National Cancer Institute  National Cancer Institute  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4309  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 109  

Detection of pyruvate carboxylation and age related changes in glycolysis in human brain using hyperpoplarized 13C MR spectroscopy

Author:Albert Chen  Casey Lee  Benjamin Geraghty  William Perks  Hany Soliman  Charles Cunningham  

Institution:Ge Healthcare  GE Healthcare  Sunnybrook Health Sciences Centre  Sunnybrook Research Institute  University of Toronto  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4301  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 101  

Differentiating Radiation Necrosis from Brain Tumor Using Hyperpolarized Carbon-13 Metabolic MRI

Distinguishing metabolic signals of liver tumors from surrounding liver cells using hyperpolarized 13C MRI and Gadoxetate

Author:Shubhangi Agarwal  Jeremy Gordon  Natalie Korn  Robert Bok  Cornelius Morze  Daniel Vigneron  John Kurhanewicz  Michael Ohliger  

Institution:University of California  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4305  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 105  

Effect of Opening the Blood-Brain Barrier with Focused Ultrasound on 13C Hyperpolarized Imaging in Rat Brain

Ex-vivo investigation of renal metabolic heterogeneity using hyperpolarized [1-13C]pyruvate MRI: a novel renal perfusion device

Author:Christian Mariager  Esben Hansen  Sabrina Bech  Anders Munk  Mads Lyhne  Karsten Søberg  Peter Nielsen  Steffen Ringgaard  Christoffer Laustsen  

Institution:Aarhus University  Aarhus University Hospital  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4321  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 121  

Feasibility and Reproducibility of Imaging Brain Metabolism Using Hyperpolarized 13C Pyruvate in Humans

Flow attenuation and saturation-recovery to discriminate between intracellular and inflowing species in renal hyperpolarized 13C MRS

Author:Alice Radaelli  Rolf Gruetter  Hikari Yoshihara  

Institution:École Polytechnique Fédérale de Lausanne (EPFL)  University of Geneva (UNIGE)  University of Lausanne (UNIL)  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4320  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 120  

Hyperpolarised [1-13C]pyruvate imaging of response to Bevacizumab

Author:Richard Mair  Alan Wright  Kevin Brindle  

Institution:CRUK Cambridge Institute, University of Cambridge  University of Cambridge  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4310  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 110  

Hyperpolarized 13C MRI Cellular Transport Modeling

Author:Zijun Cui  Xucheng Zhu  Renuka Sriram  Zhen Wang  Peder Larson  

Institution:Shanghai Jiao Tong University  University of California, San Francisco  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4314  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 114  

Hyperpolarized 5-13C-Glutamate metabolism as a biomarker of IDH1 mutant glioma response to temozolomide therapy

Hyperpolarized Dihydroxyacetone Metabolism in the Mouse Liver Under Physiological Perfusion Conditions

Author:Mukundan Ragavan  Alan Carter  Daniel Downes  Anthony Giacalone  Keith Michel  James Bankson  Matthew Merritt  

Institution:MD Anderson Cancer Center  University of Florida  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4318  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 118  

Investigating the Impact of Hypoxia on Lung Metabolism using Hyperpolarized Carbon-13 MRSI

In-Vivo Metabolism Differences of Multiple Body Parts using Hyperpolarized [2-13C]pyruvate

Author:Jian-Xiong Wang  

Institution:UT Southwestern Meidcal Center  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4303  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 103  

Lactate production but not pool-size is altered in infiltrative mouse model of human GBM: a 1H MRS and hyperpolarized [2H7,13C6]D-glucose study

Metabolism of hyperpolarized [1-13C]pyruvate in isolated perfused kidneys

Mitochondrial redox imaging of NASH animal model using in vivo Dynamic Nuclear Polarization MRI

Author:Fuminori Hyodo  Ryosuke Nakata  Hinako Eto  Tomoko Nakaji  Masaharu Murata  Tatsuya Naganuma  Makoto Hashizume  Masayuki Matsuo  

Institution:Gifu University  Japan Redox Inc.  Kyushu university  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4324  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 124  

Non-invasive detection of toxin-induced inflammation in the mouse brain using hyperpolarized 13C MRSI

Author:Lydia Le Page  Caroline Guglielmetti  Brice Tiret  Myriam Chaumeil  

Institution:University of California, San Francisco  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4322  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 122  

Per-deuteration does not affect metabolic rates of hyperpolarized pyruvate in the isolated heart

Author:Alexander Funk  Chalermchai Khemtong  Nesmine Maptue  Dean Sherry  Craig Malloy  

Institution:UT Southwestern Medical Center  UT Dallas  Veterans Affairs North Texas Healthcare System  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4319  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 119  

Probing multiple metabolic pathways in vivo with 1H-decoupled 13C-MRS of hyperpolarized [2-13C]dihydroxyacetone

Pyruvate dehydrogenase kinase knockout restores hepatic pyruvate oxidation in STZ-induced diabetic mice as revealed by hyperpolarized 13C-MRI

Quantification of In Vivo Saturation Kinetics of Co-Polarized [2-13C]Pyruvate and [1,4-13C2]Fumarate in Rat Liver Using Dynamic 3D-Spiral CSI with Alternate Spectral Band Excitation

Author:Maninder Singh  Aditya Jhajharia  Dirk Mayer  

Institution:University of Maryland Baltimore  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4317  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 117  

Rapid Visualization of the Effects of Lactate Dehydrogenase Inhibition in Breast Cancer using Hyperpolarized Pyruvate

Author:Cody Callahan  Manushka Vaidya  Olmo Sonzogni  Jocelin Pinto  Pankaj Seth  Gerburg Wulf  Aaron Grant  

Institution:Beth Israel Deaconess Medical Center and Harvard Medical School  

Session Type:Digital Poster  

Session Date:Wednesday, 15 May 2019  

Session Time:16:45  

Session Name:Hyperpolarized C13 Imaging: Novel Applications  

Program Number:4306  

Presentation Time:16:45   

Room Number:Exhibition Hall  

Computer Number:Computer 106  

Research Polarizer Quality Control Metrics and Resulting SNR in Human Prostate Cancer Patients