Connectomics analyses play a major role in our understanding of the human brain organization and function. In this talk, I will present the concepts, methods and applications of a widely used approach to examine brain organization: connectivity-based parcellation (CBP). I will then introduce the concepts and methods of connectivity-based psychometric prediction as an approach capitalizing on interindividual variability in brain and behavior to study the relationship between brain organization and behavioral functions. I will here focus on the prediction of psychometric data based on resting-state functional connectivity (rs-fMRI).