MRI technology is extremely powerful but relatively expensive, somewhat unreliable, complex to operate, and (thus) often poorly utilized. While most institutions attempt to optimize MRI for specific use cases, the variations in “optimal” protocols across institutions (and radiologists) reflect a lack of objective criteria for diagnosis. Arguably, even the standardization of exam slot times reflects institutions’ need for efficient scheduling, rather than optimal allocation of resources to individual patient care. This all presents great opportunity for increasing the impact of MRI on patient care while simultaneously reducing the cost of healthcare with more efficient, targeted, accurate and actionable diagnostic scans.