Synopsis
The design of proper RF pulses for any magnetic resonance experiment is absolutely critical. Here we discuss basic properties of RF pulses such as the flip angle, duration, and amplitude, and extend into pulse design covering topics such as spatial localization, Shinnar Le-Roux pulses, adiabatic pulses, multi-band pulses and multi-dimensional pulses. Practical design and simulation is emphasized.
Target Audience
The
target audience for this talk is junior physicists and engineers who are
interested in understanding and designing RF pulses. As RF pulses are a
critical portion of a pulse sequence those who are interested in pulse
sequences will also benefit.Outcome/Objective
The
information provided in this lecture provides a framework for the development
of many pulses, from basic Shinnar-LeRoux (SLR) pulses to more advanced 2- or
3-dimensional adiabatic pulses. The talk is structured around how the different
properties of RF pulses (flip angle, spatially selectivity, adiabaticity)
relate to one-another, and how they can be used. This will enable a deeper
understanding of how RF pulses operate, and help the audience in designing and
choosing the proper pulses for their own experiments. At the end of this talk
the audience will have a clearer understanding of the different types of RF
pulses, and how to choose the most appropriate pulses for their experiments.Methods
First,
the basics of RF pulses are discussed, namely the amplitude (as measured in
Tesla or micro Tesla), the duration (as measured in seconds) and the resolution
of the waveform. The Bloch equation is then discussed, as this is what dictates
how the magnetization and RF pulses interact. An intuitive solution to the
Bloch equation is presented which provides a clear understanding of how RF
pulses operate without the need for any dense mathematics. The most fundamental
quality of an RF pulse, the flip angle is discussed, with emphasis that
although 90 and 180 degree pulses are the most common they are certainly not
the only two types of RF pulses. From here spatial selectivity is discussed,
starting with how that is achieved (through the simultaneous application of RF
pulses and gradients). This leads into the more complex and commonly utilized
SLR transform, with practical advice given on how to design SLR pulses. Then
the excitation k-space formalism is discussed, which allows for the design of
RF pulses which excite a general spatial location, as well as the concept of
multiband pulses which are used in simultaneous multi-slice imaging.
Adiabaticity is discussed, starting with the hyperbolic secant pulse then providing
a diagrammatic explanation of the Bloch equation which enables a deeper
understanding for all adiabatic RF pulses. At the end all of these concepts are
discussed in tandem, through the example of a 2-dimensional adiabatic inversion
pulse. Some practical tips regarding implementation and simulation are given. Discussion
RF pulses are a critical portion of every magnetic resonance
experiment. The proper choice of RF pulses can distinguish between a high
quality and meaningless data.Conclusions
The concepts of RF pulse design will provide a framework for
understanding broad classes of RF pulses found throughout the field. Practical
tips regarding implementation, RF pulse and simulation are provided. This will
help enable researchers to choose the proper RF pulses for their desired
applications.Acknowledgements
No acknowledgement found.References
No reference found.