Radiologists commonly encounter portal venous abnormalities. Understanding the varying appearances of acute and chronic portal venous thromboses and the associated changes of hepatic enhancement patterns is important for patient management. Furthermore, it is important to recognize that portal venous thrombosis may change the contour of the liver, and simulate cirrhosis. Congenital and acquired chronic portal vein thrombosis may lead to the development of hepatic masses, and may alter the appearance of the bile ducts and mimic malignancy.