Acceptance of a new technique generally requires that the acquisition have one or more of the following qualities: faster, more robust/reliable, improved image quality, or offers new information not previously available by other acquisition techniques. Evaluation of new imaging techniques should focus on the specific anatomy of interest or on a specific clinical question, not the overall appearance of an image. Ultimately, determination of clinical impact requires evaluation of diagnostic accuracy, clinical effectiveness and the impact on clinical decision-making. Effective development and translation of new imaging techniques into clinical care requires partnership with clinical imaging experts.