Lawrence Dougherty1, Pilla J. James1, and Anil Chauhan1
1Radiology, University of Pennsylvania, Philadelphia, PA, United States
Synopsis
The current state of
hernia repair relies heavily on clinical evaluation of patients,
which is ultimately a poor predictor of outcomes for patients going
into surgery. There are currently no reliable data, standard imaging
modalities, or guidelines available to predict successful fascial
closure in hernia repair. A method using MR tissue tagging with
synchronous displacement of the abdominal wall was developed. This
will allow analysis of the mechanical properties of muscle for
noninvasive, diagnostic tool for pre-operatively predicting
successful fascial closure in hernia repair.
Introduction
Two million abdominal
surgeries are performed annually in the United States, and ventral
hernia (VH) is among the most common and serious complications1. The incidence of VH is approximately 13%, but as high as 70%
in high-risk populations1-3. Failed repairs generate
un-closable midline defects that require mesh bridging - native
fascia cannot be closed and the mesh is ‘bridged’ across the
fascia. Bridging is a relevant and clinically meaningful outcome,
since repairs fail in 44 to 100% of cases and significant costs are
incurred4. The current state of hernia repair relies
heavily on clinical evaluation of patients, which is ultimately a
poor predictor of outcomes for patients going into surgery. There are
currently no reliable data, standard imaging modalities, or
guidelines available to predict successful fascial closure in hernia
repair. A method had been developed that allows non-invasive
assessment of muscle compliance using a device to deform the
abdominal muscle combined with MR tissue tagging.Methods
IRB approval was obtained
prior to the start of this study and was HIPAA compliant. A custom
device was built that deforms the abdominal wall muscle synchronous
with the imaging cycle. Deformation was performed using an external
device consisting of an MR compatible pneumatically actuated air
cylinder (IPS, Irvive, CA) that was mounted to an RF coil. Pneumatic
valves triggered by a timing board controlled the rates of extension
and retraction of the air cylinder piston-rod (Figure 1). Maximum extension of
the piston rod was 5 cm. The timing board also triggered the imaging
sequence, which was a 2D SPGR gated multiphase acquisition with
tissue tagging. Scan parameters were: TE=1.75ms, TR=3.9ms, FOV=320
x 210 mm, 4mm slice thickness, 6 mm tag spacing, using 5 views per
cardiac segment. The sequence was gated to the air cylinder cycle
time, which was 1800ms. The scan was performed in a breath-hold
which was 27 seconds.Results
Five imaging studies were
successfully performed on normal volunteers. The air cylinder was
able to produce sufficient deformation of the abdominal wall muscle
synchronous with the tissue tagged imaging sequence. Images from a
volunteer study are shown in Figure 2. Muscle deformation is clearly
seen in the final frames.Conclusion
MR tissue tagging with
synchronous displacement of the abdominal wall was shown to provide
measurements of muscle deformation. This will allow analysis of the
mechanical properties of muscle for noninvasive pre-operative
prediction of successful fascial closure in hernia repair.Acknowledgements
This work supported by an
RSNA Research Seed Grant.References
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