3D-Ultrashort Echo Time (UTE) sequences with 3D-kossh ball trajectory suffer from k-space trajectory deviations and ghosting artifacts due to hardware imperfections. The gradient system transfer function (GSTF), completely characterizes the gradient system as a linear and time-invariant (LTI) system. In this study, the GSTF was measured only using standard scanner hardware and was used to correct deviated trajectories in image reconstruction. This results in diminished ghosting artifacts and improve image quality.
A 3D-Ultrashort Echo Time (UTE) sequence2,3 was implemented on a 3T MR system (MAGNETOM Prismafit, Siemens Healthcare, Erlangen, Germany) and measurements were performed with a 32-channel head coil in a structural phantom and in head-measurements in-vivo. The UTE pulse sequence featured a 3D-koosh ball center-out trajectory with a quasi-random sampling order. For the UTE acquisition the following parameters were applied: TE = 0.03 ms, TR = 1.49 ms, flip angle = 2°, in- plane resolution = 2.3 mm x 2.3 mm, slice thickness = 2 mm and number of spokes = 350000. A separate GSTF of the MR system for each spatial dimension was determined using triangular input gradients4,5. In a prototype sequence, 12 different input gradients (duration 100 – 320 µs, slew rate = 180 T/m/s) were played out, and the system’s response was measured in two parallel slices of a spherical phantom. The output gradient was then calculated using the difference in phase evolution between both slices. The relevant measurement parameters were set to: TR = 5.0 s, slice thickness = 3 mm, slice gap = 33 mm, flip-angle = 90°, read-out bandwidth = 100 Hz/pixel, 60 averages.
The magnitude and phase of the relevant GSTFxx, GSTFyy and GSTFzz are shown in Fig. 1. For the GSTF trajectory prediction the nominal gradient signals $$$g_{nom}(t)$$$ were corrected using GSTF information. The corrected gradient waveforms $$$g_{corr}(t)$$$ were calculated as:
$$g_{corr}(t)=\mathscr{F}^{-1}\{\mathscr{F} \{ g_{nom}(t) \} \cdot GSTF \}.$$
Images of the structural phantom and in-vivo measurements were then reconstructed using convolution gridding with the nominal trajectory and the corrected trajectory after the GSTF-information was applied to the nominal gradient waveform.
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