The scan technique and reconstruction method presented in this work are designed to reduce the scan duration of 2D time-of-flight angiography sequences. The acquisition makes use of a sliding-slice technique that eliminates the need for steady-state prep pulses, which are needed before each slice in time-of-flight. This reduces the total scan time of a 2D spiral time-of-flight sequence by almost half, without a reduction in k-space coverage.
Purpose
Theory
In spiral scans, as the sampling window is increased, fewer spiral acquisitions are needed to fully sample k-space, however, the number of start-up cycles needed to achieve steady state remains about the same (figure 1), leaving a larger portion of the scan duration to segments that aren’t acquiring data. The approach to steady is potentially more important to spiral sequences since each interleave samples the center of k-space (figure 2). The proposed sliding-slice technique creates a sliding window of overlapping slice excitations to maintain the saturation of static signal in the majority of the imaging plane while incrementally introducing fresh magnetization at the leading edge of the window.
In the sliding-slice technique, each spiral encode is sampled at a fraction of the slice-to-slice spacing ($$$\Delta_s$$$). As the spiral encoding index is incremented, the slice location is advanced by a step of $$$\Delta_s/m$$$, where $$$m$$$ is the number of spiral encodes. This small shift in slice location creates a small overlap of each slice with its neighbor and works to incrementally saturate the static tissue at the leading edge of each slice.
Each interleave $$$j$$$ (figure2(a)) will belong to a group that is shifted by $$$\Delta_s/m · j$$$ in the slice direction. The group will have the same in-plane k-space sampling, therefore, the shifts can be undone by applying the correct linear phase in the Fourier domain of the slice dimension.
The spiral index ordering (figure 2(b)) was chosen to minimize the effects of motion related artifacts by collecting the spiral interleaves in a way that minimizes the coherence of temporally varying signal, as described in [6]. This indexing pattern only affects the in-plane spiral order. The slices advance with the temporal indexing so that the sliding-slice transitions smoothly.
Methods
Scan Parameters: The proposed method was compared to conventional spiral and Cartesian methods for 2D multi-slice imaging of the carotid bifurcation. All scans were performed on a volunteer using a 3T Philips Ingenia system with a $$$17$$$-channel head and neck coil.
Cartesian: The standard Cartesian parameters used were: $$$TR/TE=16/3.2$$$ msec, $$$20x20$$$ cm in-plane field of view (FOV), $$$3$$$ mm slice thickness with a $$$1$$$ mm slice-to-slice overlap, $$$80$$$ slices, $$$30^◦$$$ flip angle, a sampling window of $$$3.7$$$ msec and flow compensation gradients. Three Cartesian sets were collected with fully sampled k-space, and SENSE reduction factors of $$$R=2$$$, and $$$R=3$$$.
Spiral: The spiral scan parameters were: $$$TR/TE=30/3.5$$$ msec, $$$24x24$$$ cm FOV, $$$35^◦$$$ flip angle, a sampling window of $$$10.6$$$ msec, $$$27$$$ spiral interleaves, $$$3$$$ mm slice thickness with a $$$1$$$ mm slice-to-slice overlap, and $$$80$$$ slices with flow compensation gradients in the slice select direction. Two spiral sets were collected, with and without, the sliding-slices technique. Figure 3 shows the timing composition for each experiment.
Steady State: Two small spiral experiments were used to determine steady state for the aforementioned experiments, wherein the magnitude of the first sampled point of each spiral was plotted against the repetition number. The subject was a bottle of tap water.
Results & Discussion
Conclusion
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