Terence W Nixon1, Scott McIntyre1, and Robin A de Graaf1
1MRRC Yale University, New Haven, CT, United States
Synopsis
Generating additional
magnetic fields independently from the MR scanner’s hardware requires additional
controllers, current amplifiers and DC coils. Here we present the design and
implementation of a 64 channel arbitrary gradient waveform controller that can
be used to drive current amplifiers with analog inputs. We describe the controller’s
architecture and how sequences are developed. We will also discuss the
important criteria needed to synchronize the waveforms with the MR scanner. Finally,
we will show the completed controller and the first MR result.
Introduction
There has been a recent
interest in developing magnetic field shapes independent of the MR scanner’s
gradient and shim coils (1-5). This interest has been for shimming, both static
and dynamic, as well as linear and non-linear encoding. What all applications have
in common is the need for a method of defining and generating arbitrary
waveforms synchronous with the MR scanner. The requirements for the controller
are identical to the gradient controllers on the MR scanner but many more
channels are needed. The requirements include a simple and fast method of
defining and downloading the waveforms to a controller; each channel has to be synchronous
with both the MR sequence and each other and finally have the ability to drive
a whole range of current amplifiers. Here we present the complete design and implementation
of a modular 64 channel gradient waveform controller. We show both electrical
and MR results and discuss possible future system implementations.Method
Figure 1 shows a block
diagram of the system. A master controller interfaces with the main MR scanner
and defines the timing for itself and up to eight waveform boards. It is
important that a common clock is used on all boards and that they are all
synchronized to the master controller. Each waveform board contains eight
independent channels which have their own memory (8MB per channel), digital to
analog convertor and a summation amplifier so a shim offset can be applied
independently from the waveform sequence. Sequences are developed on a PC using either
the graphical user interface (GUI) or a simple text file and downloaded ahead
of the sequence via a fast Ethernet protocol. Waveforms can be defined in two
different ways: Firstly, a Dynamic Shim Updating (DSU) mode which only
generates trapezoids. Sequences are defined as a series of “events”. The user
only has to define each event’s amplitude and a global ramp time is
automatically added. This has the advantage of requiring much less memory and
communication time. Each event is played out upon the receipt of a trigger
pulse from the scanner’s pulse program and will loop back to the beginning after
a user defined number of events. Secondly, a full arbitrary waveform mode. A
sequence is built from a number of waveform blocks defined on a 4us grid.
Special commands are used so that delays and periods between shapes do not have
to be defined on the grid, thereby reducing memory and communication
requirements. A sequence is initiated with a single trigger pulse from the
pulse program. The sequence can be resynchronized with a pulse from the pulse program
during each TR to prevent any synchronization errors occurring during long
sequences. Results
Figure 2 shows two channels in DSU mode playing out a simple
four event sequence. The GUI is used to edit the sequence and then download it
to the controller. Each of the events has a ramp time of 150us added to it.
Four trigger pulses are needed to implement this sequence. Figure 3 shows a
more complex arbitrary waveform sequence output and its GUI. Only a single trigger
pulse is needed to initiate the sequence. The first channel (yellow trace)
contains two waveforms separate by a delay. The two waveforms are defined only
once in memory but the second waveform’s amplitude is halved and inverted. The
other channels each contain a single waveform. Figure 4 shows an output
waveform and the magnetic field output generated by a single DC coil out of a
48-multi-coil setup (6). The MR data was acquired
from a small 8 uL volume placed adjacent to the DC coil and measured as the
phase difference between signals acquired in the absence and presence of the
input waveform. The high fidelity and accuracy of the experimental waveform is
apparent.Discussion
A multi-channel gradient
waveform controller has been developed for the purpose of driving current
amplifiers to generate magnetic fields within a MR experiment. Figure 5 shows a
complete 16 channel controller. The unit is modular and can support up to 64
channels per controller. Multiple
controllers can be “daisy chained” together to add even more channels which are
all synchronized to the MR scanner using trigger pulses from the scanner’s
pulse program. The individual channel outputs can be connected to any set of current
amplifiers that have an analog input. This has been shown to work here with a
simple 1A multi-coil current amplifier. The
unit will also be used to drive 100A gradient amplifiers for non-linear
encoding experiments.Acknowledgements
No acknowledgement found.References
1. Hennig J, Welz AM, Schultz G, Korvink J, Liu Z, Speck O, Zaitsev M. Parallel imaging in non-bijective, curvilinear magnetic field gradients: a concept study. Magma 2008;21:5-14.
2. Stockmann JP, Ciris PA, Galiana G, Tam L, Constable RT. O-space imaging: Highly efficient parallel imaging using second-order nonlinear fields as encoding gradients with no phase encoding. Magn Reson Med 2010;64:447-456.
3. Juchem C, Nixon TW, McIntyre S, Boer VO, Rothman DL, de Graaf RA. Dynamic multi-coil shimming of the human brain at 7T. J Magn Reson 2011;212:280-288.
4. Juchem C, Umesh Rudrapatna S, Nixon TW, de Graaf RA. Dynamic multi-coil technique (DYNAMITE) shimming for echo-planar imaging of the human brain at 7 Tesla. Neuroimage 2015;105:462-472.
5. Stockmann JP, Witzel T, Keil B, Polimeni JR, Mareyam A, LaPierre C, Setsompop K, Wald LL. A 32-channel combined RF and B0 shim array for 3T brain imaging. Magn Reson Med 2016;75:441-451.
6. Juchem C, Herman P, Sanganahalli BG, Brown PB, McIntyre S, Nixon TW, Green D, Hyder F, de Graaf RA. DYNAmic Multi-coIl TEchnique (DYNAMITE) shimming of the rat brain at 11.7 T. NMR Biomed 2014;27:897-906.