Benjamin Emanuel Dietrich1, Jennifer Nussbaum1, Bertram Jakob Wilm1, Jonas Reber1, and Klaas Paul Pruessmann1
1Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Zurich, Switzerland
Synopsis
Under the
assumption that a gradient system is linear and time-invariant (LTI), accurate gradient
field waveforms can be predicted by gradient response functions. However,
time-invariance can be violated due to heating of system components. Temperature
sensors can be used to assess heating of the gradient coils. To assess the
predictability of gradient response function based on temperature measurements,
the temperature dependence of gradient response functions is analyzed using an
NMR probe based field camera and optically connected temperature sensors. From
this data a prediction model is generated and tested for its application in
image reconstruction.
Introduction
The vast
majority of advanced MR imaging methods depends on very accurate gradient
waveforms for signal encoding and preparation. Many hardware factors limit the
fidelity of these waveforms, such as eddy currents, limited bandwidth and
mechanical vibrations. Under the assumption that these systems are linear
time-invariant (LTI), the actual gradient field waveforms of an ideal input pulse
program can be calculated using gradient response functions [1–3] and be used for image
reconstruction [3]. Recent research showed that the
assumption of time-invariance can be violated under high duty-cycles presumably
due to heat up of the MR system components [4, 5]. These changes, however, are slow compared
to typical imaging readouts and may be mapped to temperature distributions as
suggested by [4]. To assess the predictability of
gradient response function based on temperature measurements we analyze temperature
related changes on an extended dataset and use the resulting model to perform gradient
response predictions over periods of weeks, solely based on response function calibration
data and temperature sensor data.Methods
In order to
measure response functions, frequency swept pulses (0-30kHz, duration:
100ms) were played out on each gradient input [2] and the corresponding field
responses were measured over a period of 1.1s. A recently proposed
continuous field monitoring method [6], based on rapidly re-excited sets
of NMR probes [7, 8] and a dedicated monitoring system [9] was used to capture the field
responses. This method enables fast, high SNR, single-shot field measurements over
arbitrary durations. The actual response functions were then determined by
deconvolution in the frequency domain.
Measurements
from 5 optically connected temperature sensors (casted into the gradient coil)
were used to monitor the temperature with a temporal resolution of 1 s.
In two
calibration sessions response functions were measured under various temperature
distributions, which were reached by playing out different heating gradient
waveforms as illustrated in Figure 1. This calibration data set was then
used to predict response functions in a third session from the current
temperature (Figure 1).
The
employed prediction model was based on the temperatures ($$$T$$$), the
derivative of the temperatures ($$$\dot{T}$$$) and GIRFs ($$$G$$$) from similar temperature conditions: $$$G=B_0+B_1 T+B_2 \dot{T}$$$, with $$$B_0$$$
a constant component, $$$B_1$$$ the temperature dependent components and
$$$B_2$$$ the temperature derivative dependent components, all represented in
the frequency domain. The training GIRFs ($$$G$$$) with similar temperature
conditions were selected based on their Euclidean distance to the test
temperature condition in the 5 dimensional temperature space spanned by the 5
temperature sensors. The radius of this selection range was set to 8 °C.
The quality
of the predicted GIRFs was assessed by image reconstruction on simulated data.
Therefore, four different k-space trajectories were employed. A nominal
trajectory (resolution = 1mm, FOV = 256mm, duration = 59ms,
SENSE 2.32) as well as “cold state”, “hot state” and “hot state temperature
predicted” trajectories that were calculated from the corresponding response
functions and the gradients of the nominal trajectory. Thereafter NMR signals of an object were first simulated based on the “hot state” trajectory $$$k(t)$$$
as $$$M(t) = s(x)A(x) e^{i k(t)x}$$$. With $$$k$$$ being the k-space
coordinates, $$$s$$$ coils sensitivities and $$$A$$$ the objects transverse magnetization. Subsequently images
were reconstructed on a 256x256 matrix with all four trajectories.
Image reconstruction was based on the iterative SENSE reconstruction described
in [10, 11].
All measurements were performed on a Philips
Achieva 7T MRI system (Philips Healthcare, Cleveland, USA).
Results
Figure 1
shows that heating curves look quite different depending on the input gradient
waveforms. The smallest overall heat-up is observed on the z-channel, which is probably
due to direct water cooling of the conductor.
The
deviations of the observed response functions under different temperatures span
a range of up to 4% at resonance frequencies (most likely mechanical) and
up to 5‰ in the most relevant band for imaging sequences of up to
5kHz (Figure 2).
It can be
seen in Figure 4 that all response function based trajectories deviate
significantly from the nominal trajectory due to the bandwidth limitations
imposed by the system. The temperature predicted one does not fully match the
one calculated with the “hot state” response function, but it gets
significantly closer than the “cold state” trajectory. A clear improvement of
the temperature based prediction compared to the “cold state” and nominal can
be observed in the corresponding images (Figure 5).Discussion / Conclusions
Time-invariance
violations of gradient response functions due to temperature changes were
analyzed and response functions of “hot” system states successfully predicted
using a model based on previously acquired calibration data at similar
temperature conditions.Acknowledgements
No acknowledgement found.References
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