Synopsis
161
Mapping the human brain structures and functions and elucidating their
relationships with cognitive behaviors is one of the most challenging
yet intriguing missions. An overarching goal of the Human Connectome
Project (HCP) is to tackle this amazingly complex
problem to explore the unique neural underpinnings of human cognitions
and to reveal what makes individuals different from each other. An
immediate goal of the HCP is a database of over a thousand healthy
subjects1,
including high-quality multi-modality in vivo neuroimaging data, as
well as the comprehensive demographic, genetic, and behavioral
information. The database also included the state of art diffusion MRI
(dMRI) data generated on the Connectome Scanner equipped
with the 300mT/m gradient system2,
and will be expanded to include neuroimaging and behavioral data of
various age cohorts across the lifespan.
Parallel to the acquisition and sharing of the “big data”, the
technical aspects of the project have focused on developing a series of
normative procedures of data generation, preprocessing and analyses3-8.
Acknowledgements
The work is supported by funding from the National Institutes of Health Blueprint Initiative for Neuroscience Research Grant U01MH093765.
We acknowledge Siemens Healthcare for constructing the 300mT/m gradient system as well as the 3T platform.
References
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