Synopsis
This talk will provide an overview on current methods in prospective motion correction for head MRI. It includes both optical motion correction methods as well as NMR-based methods. A selection of currently available technologies will be discussed, including moiré phase tracking, self-encoded optical markers, and gradient tones.Talk Overview: Adaptive Motion Correction for Head MRI
In this talk, motion correction methods for head MRI are presented that rely on signals from external sensors as opposed to ones from tissue magnetization. Head motion is primarily rigid, that is, the head's pose can be captured by determining three rotational and an additional three translational degrees of freedom, which simplifies the motion correction task to a degree that enables the use of markers as a proxy for the head pose. This shifts the head pose encoding from pulse sequence design to marker tracking. This shift enables independent MR image encoding and pose tracking, whose consequences are manifold and the content of this talk. Finally, once the head pose has been faithfully estimated, the sequence geometry must be adapted using the updated head pose information, which requires the transmission of the geometry information to the real-time sequence controller.We will cover the elements of a prospective motion correction system and present current solutions and remaining challenges:
1. Marker and Receiver Subsystem
2. Signal Encoding Principles
3. Signal Processing Chain
4. Transmission of the Geometry Updates to the Sequence Controller
Marker and Receiver Subsystem
Optical markers and cameras are
the most commonly employed motion correction systems in head MRI, and
several different implementations thereof have been devised. This
technology has matured since the early publications An early system
published in [1] is based on a set of four reflective markers whose
individual positions were recorded with a camera standing outside of the
scanner bore. The markers are attached to a bite bar in order to ensure
a rigid configuration among themselves as well as the skull of the
subject.A second approach [2] relies on a single marker whose relative
position to an initial reference is encoded in moiré patterns, i.e. the
motion-dependent interference pattern between two gratings. The camera
system employed in [2] was now placed inside the scanner bore, which
proved to be more robust and practical compared to the camera systems
outside the bore.Another approach that was presented in [3,4] employs a
checkerboard marker that is recorded with an in-bore camera placed
directly on the head coil. An important feature of that type of marker
is a digital code printed on checkerboard pattern, which provides
tracking stability in cases when the line-of-sight from the camera to
the marker is partially interrupted.This talk will cover the individual
strengths and weaknesses of the different optical marker designs and
their technology.NMR-based markers will be discussed as an important
alternative to optical systems. They consist of a set of small NMR
active droplets (diameter ~ 0.5 - 2 mm) whose position is encoded with
dedicated gradient waveforms, which modulate the phase of the droplet's
signal as a function of position. The marker's signal is received by a
small RF coil that is tightly wrapped around the droplet and connected
to tuned RF receive hardware.NMR Markers for motion correction were
developed as early as 1998 by Derbyshire et al. [5], but gained traction
only with the first in-vivo data presented by Ooi and Krueger [6,7]. A
step forward in NMR marker design was done by Barmet et al. [8] whose
markers, or "field probes", were applied to motion correction by
Haeberlin et al. in 2013. The sensitivity of their field probes was high
enough to enable two things that will be covered in this talk: First, a
novel position encoding method that enabled concurrent field probe
localisation and image encoding ("gradient tones"), a feature that had
not been possible with the previous approaches. Second, they allow to
additionally correct for imperfections in the image encoding field by
field monitoring that is performed concurrently to the image
acquisition.We will give an overview on how NMR marker systems are
designed and applied in practice.
Signal Encoding Principles
In this part
of the talk, we will discuss how the different markers actually encode
the head pose. For the optical methods, we will include the
functionalities of the moiré-patterned marker as well as the
checkerboard marker. For the NMR-markers, we will discuss the sequence
module using static gradients as well as methods employing dynamic
gradient waveforms such as gradient tones.
Signal Processing Chain
An
important aspect of all motion correction system is the speed at which
the position updates can be computed. We will discuss signal processing
aspects for both the optical methods, which contain 2D pattern
recognition algorithms, as well as NMR-based methods, which process 1D
NMR signals.
Transmission of the Geometry Updates to the Sequence
Controller
An overview on how the geometry updates are fed
back to the MR system will be presented. The discussing includes the
communication protocol between the motion correction system and the MR
scanner, and the incorporation of the updated geometry information into
the running MR sequence.
Acknowledgements
The author thanks his colleagues at the IBT, in particular Prof. Dr. Klaas Pruessmann, Dr. Lars Kasper, Dr. Christoph Barmet, Dr. David Brunner, Alexander Aranovitch, and Dr. Bertram Wilm for insightful discussions.
The author gratefully thanks Drs. Murat Aksoy and Julian Maclaren for helpful discussions regarding the optical motion correction technique and the courtesy of providing figures for this talk.
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