Synopsis
Paediatric cardiac disease is often complex, requiring
comprehensive anatomical and hemodynamic assessment. C Paediatric
cardiac disease is often complex, requiring comprehensive anatomical and
hemodynamic assessment. Cardiac MRI offers a reference standard method of
assessing the cardiovascular system. However, conventional cardiac MRI can be
difficult to perform on children due to poor patient compliance. Therefore, accelerated
real-time imaging techniques are increasingly used. These will be discussed
with particular reference to studies that have demonstrated proven benefit in
the pediatric population. Target Audience
The target audience
are clinicians involved in pediatric cardiac imaging and scientists involved
in development and optimization of cardiac MR for use in children
Outcome/Objectives
At the end of this session the
participants should have a better understanding of the use and power of cardiac MR in the assessment of paediatric and congenital cardiac disease.In addition, they should be made aware of the problems associated with
pediatric cardiac MRI and current and possible future solutions.
Purpose
The uses of cardiac MR in children will be reviewed. In
particular, conventional techniques for assessment of ventricular volumes,
blood flow and anatomy will be addressed. Benefits of these techniques over
other imaging modalities (such as echocardiography and x-ray angiography) will
be discussed.
The main problem associated with performing cardiac MRI in children; namely poor patient compliance will be addressed. Specifically, children often have difficulty complying
with breath hold instructions and dislike being in the scanner environment.
Further problems are: a) complex disease requiring comprehensive anatomic and
hemodynamic assessment, b) high heart rates requiring high temporal resolution
imaging and c) small cardiovascular structures requiring high spatial
resolution imaging. Currently, the conventional solution to these problems is
general anesthesia, which is associated with some risks to the child and is a costly
procedure for the institution. Thus, new approaches are required.
Methods
These problems can be solved by removing the
need for breath holds and by reducing total acquisition time. One method by
which breath-holds can be eliminated is to use real-time imaging. However, due
to the nature of the pediatric cardiovascular system it is necessary to acquire
data at high spatial and temporal resolution. This limits the use of
conventional real-time imaging. Recently
new fast imaging techniques have revolutionized real-time imaging, allowing
high spatial and temporal resolution acquisitions. This is particularly true of
methods that utilize k-t techniques
and compressed sensing. In this session, the development of accelerated
real-time cardiac imaging will be reviewed. Specific time will be spent on
reviewing methodologies for ventricular function and flow quantification as
well as time resolved angiography. Another method of removing the need for
breath-holds is to use motion correction. The use of conventional navigators
will be addressed with the use of self-navigation being highlighted. This will
include a discussion of the different methods of measuring respiratory motion
form the raw MR data itself. In addition, the benefits of motion correction
will be described and the utility of such techniques for 3D and 4D imaging.
Finally, simple methods of improving the patient experience will be described
to aid current practice.
Results
There will be a wide discussion of studies that
have utilized accelerated techniques in children. In particular, techniques
that have resulted in a shift in types of children that can undergo cardiac MRI
will be described. This will include case studies where new MR techniques have
changed clinical practice, for instance in pediatric pulmonary hypertension.
Cost benefit analysis of these new accelerated techniques will also be
discussed and compared with other conventional imaging techniques such as
echocardiography. Finally, new techniques that may have an important role in
pediatric cardiac imaging will be discussed. This will include a discussion of
4D flow acquisitions, their benefits, problems and possible uses.
Discussion
The future of pediatric cardiac imaging will be
discussed with specific consideration given to the costs related to this
imaging technique within shrinking health care budgets. The development of
disruptive new technologies and their capacity to reduce costs and improve
patient experience will be described.
Conclusion
To conclude, cardiac MR has an important role to
play in the diagnosis and management of pediatric and congenital heart disease.
Conventional imaging provides a reference standard method of assessing cardiac
function, blood flow three dimensional anatomy. However, in children new accelerated techniques are
important to improve patient compliance and reduce costs. With these new technique it may be possible to perform rapid throughput low cost MR that may replace older and less comprehensive imaging modalities.
Acknowledgements
No acknowledgement found.References
No reference found.