Synopsis
The development of hybrid PET/MRI imaging devices provides new perspectives in cardiovascular imaging. While these two imaging modalities (PET and MRI) have gained well-established diagnostic value in clinical practice, the ability to acquire both modalities in a single session opens new perspectives in workflow and in assessment and quantitative evaluation of cardiovascular diseases. The development of new PET tracer will certainly add to the value of clinical applications of hybrid PET/MRI in the futur Target
audience
This talk is intended
to radiologists and cardiologists interested in hybrid and molecular imaging
techniques applicable to cardiovascular investigations
Outcome/Objectives
The goal of this
presentation is to report recent developments of PET/MRI hybrid imaging and its
potential applications in cardiovascular imaging
Introduction and purpose
Both PET and MRI techniques have gained
tremendous potential in clinical assessment of cardiac and cardiovascular
diseases. While providing complementary information these two techniques are
often both needed to answer specific questions and evaluate complex clinical
presentations. The ability to acquire both imaging data from PET and MRI
modalities offers a promising perspective for more efficient and potentially
more accurate assessment of
cardiovascular diseases.
Methods and techniques
This presentation
will review the evolution and current state-of-the-art hybrid imaging technology
applicable to cardiovascular imaging. Advantages and potential drawbacks of
integrated hybrid PET/MR devices will be presented and discussed
Results
Several
groups have already reported the benefits and positive results of acquiring
multimodality imaging data on hybrid PET/MR devices in applications such as assessment
of myocardial viability, quantitative evaluation of stress induced ischemia, myocardial
regeneration and evaluation of inflammatory process in instable vascular plaques.
Discussion
Preliminary
data suggest that acquisition of multimodality PET/MR can have a potential
value in clinical practice, and provides more accurate and powerful support for
clinical research. Developments of new PET tracers are expected to broaden the
clinical application of this new hybrid imaging modality.
Conclusion
Clinical studies have shown the feasibility
and potential added value of hybrid PET/MRI imaging over separate acquisitions
of imaging data from each imaging modality. Further developments of PET tracers
and more controlled clinical studies will better establish the applicability of
this technique in clinical routine.
Acknowledgements
No acknowledgement found.References
(1) Ratib, O., R. Nkoulou,
and M. Schwaiger, Cardiovascular clinical applications of
PET/MRI. Clin Transl Imaging,
2013. 1(1): p. 65-71.
(2) Ratib, O. and R.
Nkoulou, Potential Applications of
PET/MR Imaging in Cardiology. J Nucl Med, 2014. 55(Supplement 2): p.
40S-46S.