Synopsis
Target Audience
1. Neuroradiologists and clinicians using neuroimaging for the assessment of TBI or employing quantitative diffusion imaging.
2. Scientists investigating TBI or the application of quantitative diffusion imaging to individual patients.
Objectives
1. Understand the conceptual basis and clinical evidence supporting the use of dMRI in the assessment of TBI.
2. Understand the present and future potential of dMRI for use in diagnosis and prognostication for TBI patients.
3. Appreciate the limitations of dMRI in the assessment of TBI patients.
Approach
This presentation will summarize the growing evidence base for the use of dMRI to provide quantitative adjunctive diagnostic and prognostic information in the assessment of TBI patients. Focus will be on patients at the mild end of the TBI spectrum and the importance of individualized approaches to image analysis. The role of imaging in the overall diagnostic workup and management of injured patients and its limitations will be emphasized. Potential and role of dMRI in treatment trials and precision medicine approaches to TBI will be addressed.
Acknowledgements
The Dana Foundation David Mahoney Neuroimaging Program
National Institute of Health Grant R01 NS082432
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