Addressing Clinical Challenges in the Body with MRI: Contrast Agents  Hepatobiliary
Jeong Min Lee1

1Seoul National University Hospital

Synopsis

Magnetic resonance imaging (MRI) plays critical roles in the diagnosis of hepatobiliary diseases. Compared with other hepatic imaging modalities, contrast-enhanced MRI offers more comprehensive evaluation of the hepatobiliary diseases. In this lecture, I am going to discuss the key features of the different types of contrast agents, with special emphasis on pharmacokinetic features of a new hepatobiliary MR contrast agent. In addition, I will address the optimized protocols according to the type of gadolinium contrast agent. For gadoxetate disodium, the potential advantages for diagnosing liver malignancies and for evaluation of hepatocarcinogenesis will be addressed via radiology-pathology correlation and also its caveats will be discussed with typical cases.

Addressing Clinical Challenges in the Body with MRI: Contrast Agents

Magnetic resonance imaging (MRI) plays critical roles in the diagnosis of hepatobiliary diseases and staging of hepatobiliary malignancies. In this lecture, I am going to discuss the key features of the different types of contrast agents, with special emphasis on pharmacokinetic features of a new hepatobiliary MR contrast agent. In addition, I will address the optimized protocols according to the type of gadolinium contrast agent. For gadoxetate disodium, the potential advantages for diagnosing liver malignancies and for evaluation of hepatocarcinogenesis will be addressed via radiology-pathology correlation and also its caveats will be discussed with typical cases. Finally, I will review the guidelines in the imaging diagnosis of HCCs and the challenging issues that remain.

Acknowledgements

No acknowledgement found.

References

1. Guglielmo FF, Mitchell DG, Gupta S. Gadolinium contrast agent selection and optimal use for body mr imaging. Radiol Clin North Am 2014;52:637-656

2. Bashir MR. Magnetic resonance contrast agents for liver imaging. Magn Reson Imaging Clin N Am 2014;22:283-293

3. Guglielmo FF, Mitchell DG, Roth CG, Deshmukh S. Hepatic mr imaging techniques, optimization, and artifacts. Magn Reson Imaging Clin N Am 2014;22:263-282

4. Neri E, Bali MA, Ba-Ssalamah A, Boraschi P, Brancatelli G, Alves FC et al. Esgar consensus statement on liver mr imaging and clinical use of liver-specific contrast agents. Eur Radiol 2015



Proc. Intl. Soc. Mag. Reson. Med. 24 (2016)