Synopsis
Simultaneous multi-slice imaging has been employed for the DREAM B1+ mapping approach, allowing a multi-slice B1+ map to be acquired in a fraction of a second. Basic feasibility has been shown in experiments on phantoms and in vivo using a clinical 3T MRI system. The presented approach potentially allows free-breathing multi-slice B1+ mapping, freezing respiratory motion in a short single shot acquisition window. Introduction
In
high field MRI, fast and robust in vivo B
1+ mapping is an essential
prerequisite for many quantitative or parallel-transmit-based applications
(1-3). However, most B
1+ mapping techniques are too slow for a seamless
integration into the clinical workflow. Recently, the DREAM (Dual Refocusing
Echo Acquisition Mode) B
1+ mapping approach has been introduced (4), allowing the
acquisition of a 2D B
1+ map in a fraction
of a second. Moreover, a volumetric DREAM B
1+ map can be acquired in a couple of
seconds by successive acquisition of multiple slices. In the present study, the
DREAM approach is further accelerated by employing simultaneous multi-slice
imaging (5), allowing a volumetric B
1+ map to be acquired in a single shot. The
new approach has been implemented on a clinical scanner, and basic feasibility
has been shown on phantoms and in vivo.
Theory
For multiband
slice excitation, sinusoidally modulated RF pulses are employed, representing a
superposition of two or more offset frequencies, each one corresponding to a
certain imaging slice (Fig.1). Using parallel imaging, the different slices can
be unfolded from the acquired data in reconstruction. Nevertheless, the strongly modulated broad-band RF pulses potentially
suffer from long pulse duration due to the limited available peak B
1+
and SAR constraints at higher field strength. This turns out to be especially a
problem for B
1+ mapping, because these sequences are generally based on large
flip angles required for B
1+ encoding.
On the other hand,
some B
1+ mapping approaches separate the B
1+ encoding from the spatial encoding.
For instance, the DREAM sequence uses a STEAM preparation sequence for B
1+
encoding and a low angle pulse train for spatial encoding (Fig.2a), were both, an FID and a STE, are measured as separate recalled gradient echoes under a
single readout gradient lobe. Hence,
simultaneous multi-slice DREAM B
1+ mapping can be implemented combining a
non-selective STEAM preparation with a multiband imaging RF pulse train
(Fig.2b).
Methods
Phantom and in vivo
experiments on the abdomen were performed on a clinical dual-transmit 3T MRI system
(Ingenia, Philips Healthcare, Best, The Netherlands). DREAM Multiband was
implemented in the scan and reconstruction software of the scanner and used for
simultaneous B
1+ mapping of four equidistant slices (transversal orientation, slice
thickness: 10 mm, slice gap: 40 mm, FOV = 530x460mm²,
2D scan matrix = 64x56, STEAM/imaging flip angle = 50°/10°,
TE
FID/STE=2.3/3.3 ms, TR = 4.5
ms, receive coil: 28-channel anterior-posterior coil array). To improve the stability
of SENSE unfolding (g-factor), neighbouring slices were shifted by a quarter
field-of-view, which was achieved by appropriate modulation of the the RF
pulses (5). The B
1+ maps were acquired in a single shot (duration ≈ 250 ms), which allowed
acquisition of the in vivo data during free-breathing.
Results
Figure 3 and 4 show
the acquired B
1+ maps along with the underlying source images of the DREAM sequence
for the water-filled body phantom and for the abdominal acquisitions,
respectively. The B
1+ maps show the well-known shading pattern typical for quadrature
excitation at 3T. The local torso SAR level was slightly increased from 9% (conventional
multi-slice acquisition) to 13 % (simulataneous multi-slice), which is still very
moderate, especially for a B
1+ mapping scan.
Discussion
Multiband DREAM allows
for multi-slice B
1+ mapping in a fraction of a second. Thus, motion is frozen, and the acquisition can be performed during free breathing capable also to
capture dynamic processes (like respiration). The presented approach represents
an alternative to 3DREAM (6), which is based on a single shot 3D DREAM acquisition.
Multiband DREAM provides the advantage of a reduced partial volume effect, because
thinner slices may be chosen. Moreover, oversampling in z-direction is not
required, increasing the sampling efficiency of the approach. Finally, the approach
is more flexible with respect to optimizing the g-factor for the chosen coil
array by selecting appropriate phase shifts between the slices.
Acknowledgements
No acknowledgement found.References
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