Thomas Koesters1, Ryan Brown1, Tiejun Zhao2, Mattias Fenchel3, Peter Speier3, Li Feng1, Yongxian Qian1, and Fernando Emilio Boada1
1Radiology, New York University, New York, NY, United States, 2Siemens Medical Systems, Malvern, PA, United States, 3Siemens Medical Systems, Erlangen, Germany
Synopsis
We demonstrate the use of an external RF signal as a mean to provide motion tracking information for motion-state sorting of k-space line during dynamic MRI scans.Introduction
The introduction of simultaneous MR/PET scanners has, for the
first time, provided a synergistic imaging platform where the simultaneously
acquired dual-modality data can be used to provide significant improvements in
image quality, interpretation and quantification. Motion correction stands as one application where immediate
benefit can be garnered from the use of such synergies. Motion correction of
PET images relies on MR-based motion tracking information that can be used to
sort the PET listmode data into different motion states or gates. The MR images
corresponding to these gates are then used to modify the system matrix and
produce motion-corrected PET images. Prior implementations of this approach
have relied on the use of a self-navigated sequence, such as a stack of stars
[1], where the motion tracking information is derived from the center of
k-space. While effective, however, this approach only allows the correction of
the listmode data acquired when the motion tracking sequence is used. Recently,
it has been demonstrated that self-refocused [2] MR signals or signatures of
coil load variations [3,4] can be used to monitor respiratory, and sometimes,
cardiac motion. In this work we demonstrate that the use of a reference RF
signal (the pilot tone, PT) can be used, as proposed in [5], as an effective
means to identify individual motion states throughout the duration of an entire
MR/PET examination.
Methods
The
PT navigator approach was implemented on a Siemens MAGNETOM mMR (Siemens
Healthcare, Erlangen, Germany) using a 2cm surface coil (Fig 1),
which was placed outside the bore of the magnet. The coil was driven by a
signal generator with -20dBm amplitude. The PT frequency was between 7 and 50Khz
away from the center frequency of the scanner (123.216MHz) to avoid interference
with the desired MRI data. Data were acquired with both conventional gradient
echo (TR/TE=20/10ms, BW=260Hz/Pixel, 1x5mm slice) as well as a golden angle
radial imaging (RI) in-house-modified prototype sequence (TR/TE=7.92/4.94ms,
BW=680Hz/Pixel, 48x6mm slices, 2002 radial views) equipped with an additional
rosette [6] navigator readout, which allows for comparison of the PT navigator
to the conventional k-space center self-navigation [7] and coil fingerprinting
approaches [2]. The PT data from different coils in the receive array were used
to sort the measured echo into motion 'bins'. These motion bins were then used
to reconstruct the images corresponding to the different motion states.
Results
Figure 2 shows a GRE image from a normal human volunteer acquired while
using the PT signal to monitor the motion throughout the scan. A plot of the
temporal variation of the PT signal illustrates that the variations in its
amplitude are correlated to the motion of the chest cavity. Further analysis of
this signal allows the synthesis of motion bins from which individual motion
states can be reconstructed (Figure 3). Use of the rosette-navigated RI
sequence allows exclusive monitoring of the motion signal via the rosette
readout (Figure 4). Fourier analysis of this signal demonstrates the presence
of a respiratory peak (Figure 5). This signal correlates well with the tracking
signal from the center of k-space (Figure 6)and can, likewise, be used to generate motion
bins (Figure 7) from which 3D motion states can be reconstructed (Figure 8).
Conclusions
We
have demonstrated that an external RF signal, as proposed in [5], can indeed be
used to provide effective respiratory motion tracking information in real time.
The technique is straightforward to implement, requires minimal hardware, and
is transparent to the pulse sequence since specialized navigator modules are not
required. Integration of this tracking signal with MR
image reconstruction via sorting into motion bins is compatible with most MR
sequences and can provide a means to fully navigate an entire MR/PET
examination.
Acknowledgements
Supported in part by PHS Grant P41 EB 017813References
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[5] P. Speier et al. Proc. ESMRMB 2015, 129: 97-98.
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