Due to the low bandwidth of the refocusing pulses of the Point-Resolved Spectroscopy (PRESS) sequence at short echo times there are larger chemical shift displacement errors (CSDE) at high B₀ field (≥ 3T). The use of pairs of adiabatic selective refocusing pulses within the semi-LASER sequence^1-3 reduces the CSDE and increases the B₁-robustness. To achieve a short echo time ≤ 30ms short RF pulses with high B₁ amplitude as well as short crusher gradients with high amplitude have to be used. A previously reported crusher scheme¹ reduces unwanted coherence signals with an optimized set of crusher gradients. Rotation of the prescribed voxel can lead to higher gradient amplitudes on the physical axis that can result into values above the maximum gradient strength depending on system constraints. A common way to prevent this is to set the maximum gradient strength on each logical axis for the worst case of a rotation of 45° in each direction leading to a reduction of the maximum allowed gradient strength by a factor of √3 and therefore to longer crusher gradients if the area under the crusher gradients should be kept constant. The goal of this work was to implement an algorithm that keeps the areas of the crusher gradients constant and takes the rotation of the voxel into account to give shortest possible TE for any prescription under the constraint of maximum gradient strength on each physical axis.The semi-LASER sequence was implemented following the crusher scheme described in¹ (Fig. 1). An asymmetric slice selective excitation pulse (bandwidth 3.7kHz, 4.2ms pulse duration) and adiabatic refocusing pulses with a trapezoid amplitude envelope² (bandwidth 8kHz, 4.5ms pulse duration) were used. The implemented optimization algorithm kept the areas of the crusher gradients constant. A rotation of the voxel is defined by the rotation matrix that transform the gradient amplitudes from the logical (read, phase, slice) into the physical coordinate system (x,y,z). With this rotation matrix the gradient amplitudes in the physical coordinate system were calculated and checked against the constraint of maximum gradient strength in each of the 5 sections (Fig. 1). In case of a violation, first the crusher gradient that was shortest in this section got stretched, if this still led to a violation all 3 crusher gradients in that section got stretched. Phantom (GE MRS sphere) and in-vivo experiments were performed on a 3.0T MR750w system (GE Healthcare) with a maximum gradient strength of 33mT/m and a slew rate of 120T/m/s. Acquisition protocol: 2x2x2cm³ voxel size, 32-step phase cycling, 64 averages.Table 1 shows crusher amplitudes in logical and physical coordinate system as well as the inter-pulse times for various prescriptions. The minimum TE of 29ms extends slightly with increasing angulation of the voxel in multiple directions. Fig. 2 shows the corresponding phantom spectra and Fig. 3 in-vivo spectra of a left anterior white matter voxel.In the proposed crusher scheme of the semi-LASER implementation especially the crusher gradients after the last adiabatic refocusing pulse have high amplitudes on all 3 axis. Even under the constraint of a maximum gradient strength that is close to this amplitude the implemented algorithm just slightly increases the minimum echo time from 29ms to 30ms for the worst case of rotation of the voxel by 45° in all 3 directions but keeping it at the minimum echo time for most common angulations and 10% shorter compared to the common way of reducing maximum gradient strength by a factor of √3 (29ms vs. 32ms).