Abdominal FASE-DWI
Takeshi Yoshikawa1, Katsusuke Kyotani2, Yoshiharu Ohno1, Yoshimori Kassai3, Hisanobu Koyama4, Kouya Nishiyama2, Shinichiro Seki4, and Kazuro Sugimura4

1Advanced Biomedical Imaging Research Center, Kobe University Graduate School of Medicine, Kobe, Japan, 2Radiology, Kobe University Hospital, Kobe, Japan, 3Toshiba Medical Systems Co., Otawara, Japan, 4Radiology, Kobe University Graduate School of Medicine, Kobe, Japan

Synopsis

To reduce distortion on abdominal EPI-DWI, we developed Fast Advanced Spin Echo (FASE)-DWI for abdominal 3T imaging. We found FASE-DWI can provide additional diagnostic information in evaluation of various abdominal diseases and be used as an alternative to EPI-DWI.

INTRODUCTION

In current abdominal MRI, DWI is one of the most important techniques and routinely used worldwide.

However, problems still remain such as poor image quality and distortion due to air in lung or intestinal, or outside the body, especially when using single-shot EPI at 3T.

To solve this problem, we developed Fast Advanced Spin Echo (FASE)-DWI for abdominal 3T imaging.

PURPOSE

Our purpose was to assess fast advanced spin echo (FASE)-DWI in the abdomen.

MATERIALS & METHODS

52 patients (32men, 20women, mean: 69.4years), who were suspected to have hepato-biliary-pancreatic malignancy and underwent 3T-MRI, were enrolled. FSE-T2WI, SE-EPI-DWI, and FASE-DWI were obtained. Amount of abdominal gas and ascites was recorded using a 5-point scale. Anteroposterior (AP) and right-to-left (RL) abdominal diameters were measured on the slice with most severe image distortion and diameters of the right upper liver near the diaphragm were measured. Correlation analyses were performed. Image quality and severity of image distortion were assessed using a 5-point scale on EPI-DWI and FASE-DWI, and compared. Regression analyses were done to estimate factors for low image quality and severe distortion. Malignant lesion (n=39) conspicuity was assessed separately on EPI-DWI and FASE-DWI, and compared. Diagnostic confidence for malignant lesion was compared between EPI-DWI alone and EPI-DWI+FASE-DWI.

RESULTS

Correlation coefficient was the highest between T2WI and FASE-DWI for all the diameters. Lower correlation coefficients, indicating more severe distortion, were observed in abdominal AP direction and right liver AP direction on EPI-DWI. Image distortion was significantly more severe on EPI-DWI (p<0.0001). There was no significant difference between overall image quality and malignant lesion conspicuity. Age, sex, and gas were found to be significant factors for image quality on EPI-DWI (0.047, 0.004, 0.018), and sex and AP diameter were significant factors for image quality on FASE-DWI (0.005, 0.043). Diagnostic confidence was significantly higher on EPI-DWI+FASE-DWI (0.022).

SUMMARY & DISCUSSION

Quantitative Analysis

Distortion was reduced on FASE-DWI.

Qualitative Analysis

No significant deference in image quality.

Distortion was reduced on FASE-DWI.

FASE-DWI was useful in the abdominal parts near air.

Image quality was better in young men on both.

Image quality on EIP-DWI was significantly affected by abdominal gas.

Lesion Assessment

Conspicuity is similar both on EPI-DWI and FASE-DWI.

Diagnostic confidence was improved on EPI+FASE.

CONCLUSION

FASE-DWI can provide additional diagnostic information in evaluation of various abdominal diseases and be used as an alternative to EPI-DWI.

Acknowledgements

No acknowledgement found.

References

•There are only a few reports on application of FSE/TSE-based DWI technique to abdominal field.

FASE-DWI

Ohno Y, et al. EJR 2015 (Lung CA, N-staging)

Kito S, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006(head & neck abscesses)

Non-EPI-DWI

Jin N, et al. JMRI 2011 (kidney, SPLICE)

Deng J, et al. MRM 2008(upper abdomen, SPLICE·PROPELLER)

Other organs: brain, spinal cord, prostate, muscle-skeletal, etc.

Figures

Post-op Recurrent HCC

Image quality is improved on FASE. Tumor distortion and conspicuity is improved.


Liver Abscess

Image quality & distortion are improved on FASE. Conspicuity of abscess in L lobe is improved.


Pancreatic CA

Image quality is improved on FASE. Lesion conspicuity is similar on FASE & EPI.




Proc. Intl. Soc. Mag. Reson. Med. 24 (2016)
3879