Eugenia Cabot1, Earl Zastrow1,2, and Niels Kuster1,2
1IT'IS Foundation, Zurich, Switzerland, 2ETHZ, Zurich, Switzerland
Synopsis
A study of in
vivo radiofrequency exposure of a group of human models to a reduced set of
birdcages that cover clinical scanner variability was performed at 64 MHz,
with a view to the assessment of implant safety during magnetic resonance
imaging. Finite-difference time-domain simulations were run for combinations of
human model/landmark/birdcage for quadrature fed coils representing closed-bore
systems with respect to RF exposure. The evaluation of the E-fields for the Tier 3 of TS109741
shows large variations in the tangential E-field values obtained with the
different coils.Introduction
Magnetic resonance imaging (MRI) examinations of
patients with implanted medical devices comprises health risks. In particular, radiofrequency
(RF) induced heating due to coupling of RF fields with the metallic parts of
the implant could occur in the tissues surrounding the electrodes. To overcome
this hazard, only patients implanted with devices labeled by regulatory bodies
as “MRI safe” should be scanned. The safety of implants in an MRI environment
is assessed by a combination of experimental and numerical techniques
1.
The latter include the evaluation of the fields induced in patients exposed to RF
fields during MRI examinations. The absorption of RF fields by the human body during
an MRI examination depends on
many factors, e.g., the frequency,
coil dimensions, coil polarization, coil topology, and positioning landmarks of
the body, among others. A dosimetric study of the in vivo RF absorption due to MRI exposure must cover the parameters of existing clinical scanners.
Methods
The objective
of this study was to develop a minimal set of numerical models of birdcages
that comprehensively represent all the commercial closed-bore systems with respect to
RF exposure. Simulations were performed on a subset of five birdcage resonators with high pass
topology, bore diameters of 600, 700, and 800 mm and rung lengths ranging from 350 to
700 mm. All birdcages were surrounded by 850 mm long cylindrical
shields. The human exposure envelope was defined for a set of
anatomical human models that represent the patient population. The models were
positioned at a series of clinically relevant landmarks that correspond to scanning
positions for imaging targets ranging from the head to the extremities
2.
The variability and uncertainty were comprehensively assessed. All birdcages were driven in quadrature at 64 MHz.
Finite-difference time-domain simulations and
post-processing were performed with Sim4Life Version 1.2 (ZMT, Zurich,
Switzerland) and SEMCAD X Version 14.8 (SPEAG, Zurich, Switzerland).
Results
All quantities reported in
this section are for a B1-field of 1 μT at the isocenter of the coils.
Only a subset of the results are shown here. Fig 1 shows the E-field
distributions in coronal (top) and axial (bottom) slices of the Ella model positioned
for thoracic imaging. Exposures in birdcages with a fixed diameter (D) of 750 mm
and lengths of 350, 500, and 700 mm (Fig 1-top, marked with white
rectangles for the coronal views) or with a fixed length (L) of 500 mm and
diameters of 650, 750, and 850 mm (Fig 1-bottom, marked with white circles
for the axial views). The coronal E-field distributions in Fig 1-top show how the
E-field level increases as the birdcage length grows for a fixed coil diameter.
In Fig 2, the coronal E-field distributions in Fig 1 plotted against the
average E-field exposure for the five coils show the correlation of coil length
and field strength. The shorter
coils produce E-field below the average, whereas the E-field for the longer
coil are in general above the average.
In the context of implant
safety, the incident fields at possible locations of a pacemaker were obtained
to determine whether a reduced
set of birdcages is valid for demonstration of the MRI safety of implants3,
4, 5. Sets of realistic clinical trajectories representing the possible
positions of the devices were generated for all models; Fig 3-left shows
examples of cardiac trajectories in Ella. For the assessment of exposures in the
patient population, the tangential E-fields for the representative trajectories
were extracted for each human model/landmark/birdcage combination. The average E-field
tangential to 300 trajectories was plotted for each landmark group and for each
of the five birdcages (Fig 3-right shows the tangential E-fields in Ella). For
cardiac exposure, the head and thorax landmarks yield the highest E-field
values. For a fixed landmark, however, the range of the obtained values is
large depending on the birdcage the body is exposed to.
Conclusion
The envelope for
in vivo MRI exposure to a set of RF birdcages that cover the
variation existing in clinical scanners has been investigated. For this purpose,
a set of simulations were performed with permutations of human model, birdcage
model, and landmark. The preliminary assessment shows large variations in the
tangential E-field values for the different coils. From the large variations
observed, we conclude that further investigations are needed to derive a
minimal set of birdcages that can be used for safety assessment of implants;
and to determine the impact of different implant types (e.g. cardiac devices,
neurostimulation devices, etc.). Future investigations need also to include variation
of B
1 polarization as a parameter in the simulation matrix.
Acknowledgements
No acknowledgement found.References
1. ISO/TS. 10974:2012. Assessment of
the Safety of Magnetic Resonance Imaging for Patients with an Active
Implantable Medical Device. ISO/TS 10974 2012.
2. Kaut Roth C. Rad Tech's Guide to MRI: Imaging
Procedures, Patient Care, and Safety, Wiley-Blackwell, Malden, 2001.
3. Zastrow E,
Capstick M, Cabot E, Kuster N. Piece-wise Excitation System for the Characterization
of Local RF-induced Heating of AIMD during MR Exposure, in the Proceedings of
the 2014 International Symposium on EMC, Tokyo, 14P2-H7.
4. Cabot E, Zastrow
E, Kuster N. Safety Assessment of AIMDs under MRI Exposure: Tier3 vs. Tier4 Evaluation
of Local RF-Induced Heating, in the Proceedings of the 2014 International Symposium
on EMC, Tokyo, 14P2-H6.