Lukas Winter1, Antonia Barghoorn1, Peter Blümler2, and Thoralf Niendorf1,3,4
1Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine, Berlin, Germany, 2Institute of Physics, University of Mainz, Mainz, Germany, 3Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin, Germany, 4MRI.TOOLS GmbH, Berlin, Germany
Synopsis
Cost effective open source
imaging (COSI) is a collaborative initiative currently building an affordable
low field open source MR scanner with the technical documentation available at www.opensourceimaging.org.
As part of this initiative uniform Halbach magnets have been evaluated in
absolute B0, field homogeneity, magnet mass and costs. Halbach quadrupoles are
introduced, that produce an adjustable constant gradient field for spatial
encoding removing the need for high power gradient amplifiers. Combining these
efforts an imaging magnet (B0=0.3T, di=180mm) design is presented that can
incorporate a Halbach gradient of 157mT/m. The results are encouraging for low
cost low field MR applications.Purpose
MRI is the most powerful
diagnostic imaging modality available. The major drawbacks are cost and
complexity, limiting its use mainly to industrialized countries and larger
hospitals
1. Multiple studies showed that there are several clinical
applications where the diagnostic value gathered from low (B
0=0.2T) field
MRI is equivalent to the costly “high” field (B
0≥1.0T) counterparts
2-6. This work investigates permanent
magnet Halbach arrangements for low cost low field imaging applications with a
focus on absolute B
0, field homogeneity, magnet mass and cost. The
concept of Halbach quadrupoles is introduced to form constant gradient fields that
can be rotated for spatial encoding removing the need for high power gradient
amplifiers
7. Technical documentation of the presented cost effective open
source imaging (COSI) magnet will be made available based upon the principles
of open source hardware at
www.opensourceimaging.org.
Methods
Magnetostatic simulations (CST) were performed to investigate a spectrum of Halbach magnet arrangements tailored
for low field MRI. To validate the simulations, a dedicated simulation setup
was compared to experimental measurements of a Halbach magnet with an inner diameter
of d
i=130mm (Fig.1a-b). After validation, B
0, magnet radius, magnet
mass as well as number of magnet units (n=16, n=20, n=24) were calculated for
different Halbach arrangements with NdFeB magnets (ρ=7.4g/cm³, B
r=1.2T)
of varying size (Fig.2a-c). Two ring configurations (Fig.3a) were implemented
that afford a uniform B
0 volume in between the rings
8. Halbach quadrupoles
are introduced to enable constant gradient fields for distinct spatial encoding.
Finally a COSI magnet was designed and characterized for extremity MRI with an inner
diameter of di=180mm.
Results
Simulation results (Fig.1c) are in
good agreement with measurements (Fig.1d). The absolute difference along an axial
B0 profile through the center of the magnet was <10% (Fig.1e) with a relative
difference <1% (Fig.1f).
Using fewer magnet units or a bigger
magnet radius increases the magnet mass under the condition of B0=const
(Fig.1d-e). A higher number of magnet units leads to improved homogeneity,
since the theoretical periodic Halbach magnetization pattern can be recreated
more accurately. Fitting the results to a single equation (for n=16 with the proportionality
factor a(m) (Fig.1f)): $$B_0(r,m)=(23.3\cdot m+0.1311)/r^3$$ allows for a quick estimate on expected B0,
magnet radius and mass.
Varying the distance of
two ring Halbach configurations allows B0 homogenization for the central region
along z-dimension (Fig.3b). For two Halbach rings (di=180mm, n=16)
the optimal simulated distance is around 87mm, which is in close agreement with
the theoretical value of $$$r\cdot \sqrt{2/3}=90mm$$$ (Fig.3c)8.
The arrangement of 16 octagonal
magnets (Br=1.0T) to a Halbach quadrupole with radius ri1≈18cm
is illustrated in Fig.4a. The field profile By (Fig.4b) shows a
rapid exponential decay in close vicinity to the magnets (Fig.4c) and a linear
decay of 50mT/m in the center (Fig.4d). Reducing the radius of the arrangement
to ri2≈13cm allows to increase the gradient strength to dBy/dy=157mT/m
(Fig.4d). With this achievement spatial encoding can be performed by means of
rotating the quadrupole instead of the whole imaging magnet1 while the gradient
strength can be adjusted changing the quadrupole radius mechanically without
the need for costly gradient amplifiers. Rotation and repositioning is feasible
with moderate efforts, since the main Halbach magnet has no net magnetic field at
the outside.
Combining all these efforts a
possible Halbach magnet (di=180mm) for extremity MRI together with Halbach
gradients (dBy/dy=157mT/m, di=270mm) is exemplified in Fig.5a. The Halbach
magnet weighs <45kg and provides an absolute B0>0.3T with a net
magnetic field of B0≈0 at the outside (Fig.5b). The homogeneity of
the Halbach magnet can be deduced from Fig.5c-f. Without any additional
shimming the 1000ppm area is (62x50)mm² as shown in Fig.5c. Along 4cm in x- and
y-direction the field deviates by 192ppm (Fig.5d) and 574ppm (Fig.5e) respectively.
Conclusion
The combination of uniform
Halbach (dipole) magnets with superimposed Halbach quadrupoles is encouraging
for low cost low field imaging applications. Utilizing quadrupoles with their excellent
gradient field linearity for efficient spatial encoding reduces rotation to the
smaller quadrupole magnets only
7 with the gradient strength being modified by
simple mechanical displacement.
Significant improvements in B0
homogeneity could be achieved under the constraints of small and light
construction for “mobile” applications. Low static magnetic fields inside B
0≈0.3T
and B
0≈0 outside the imaging volume improve safety by reducing
attraction forces of ferromagnetic objects such as medical equipment or implants.
At the same time permanent magnets don’t require a constant/stable power supply
and don’t need risk management concerning a quench. Mechanically adjustable imaging
gradients furthermore allow for significant noise reduction versus traditional
pulsed field gradients used in today’s clinical practice.
Acknowledgements
No acknowledgement found.References
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