Nikhar Kinger1, Sadhna Nandwana1, Courtney Moreno1, Kelly Cox1, and Pardeep Mittal1
1Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States
Synopsis
The liver is an important oncologic organ. Primary liver
tumors can arise from a variety of different liver components such as
hepatocytes, bile duct epithelium, neuroendocrine cells, and mesenchymal cells.
We will discuss imaging and histopathological features of primary liver tumors
and their common and uncommon mimics.Learning Goals:
1. To
demonstrate MRI characteristics of primary liver cancers in chronic liver
disease (CLD) and non-CLD and differentiating features.
2. To
describe common and uncommon mimics of primary liver cancers and
overlapping features.
3. To
describe histopathological features of primary liver malignancies and
their mimics.
4. To
demonstrate characteristics of primary liver tumors in the pediatric
population.
Background Information and Content:
This presentation includes review of MRI examinations of
patients for characterization of liver lesions in CLD and non-CLD using
dedicated MRI protocol using extracellular and hepatobiliary contrast agents
and without. MRI findings will be correlated with histopathological findings.
The liver is an important organ from an oncologic
perspective. Primary liver cancers are more common in the presence of CLD such
as cirrhosis, hemochromatosis, etc., than non-CLD. Primary liver tumors arise from
different components of the liver such as hepatocytes, bile duct epithelium,
neuroendocrine cells and mesenchymal cells. Hence we will discuss imaging and
histopathological features of hepatocellular carcinoma, cholangiocarcinoma,
cholangiocellular carcinoma, epithelioid hemangioendothelioma, angiosarcoma,
lymphoma etc. and their common and uncommon mimics such as FNH, neuroendocrine
tumors, lymphoepithelioma, extramedullary hematopoiesis, inflammatory tumors,
sclerosing hemangioma. The patient’s age is also an important discriminating
factor because some tumors occur in the pediatric age group such as
hepatoblastoma, mesenchymal hamartoma, infantile hemangioendothelioma etc.
Summary:
MRI has evolved into a vital diagnostic tool due to its
excellent intrinsic soft tissue contrast, multiplanar capabilities, and lack of
ionizing radiation. These factors significantly contribute to the diagnostic
accuracy, successful management, and follow up.
Acknowledgements
No acknowledgement found.References
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