Miniaturized MRI System for Diagnosis of Samples of Low Physical Dimensions using Piezoelectric Receiver and Transmitter
Dhiraj Sinha1 and Shao Ying Huang1

1Engineering Product Development, Singapore University of Technology and Design, Singapore, Singapore

Synopsis

An MRI system at small physical dimensions can be developed using a piezoelectric-microcantilever system with the capability of sensing magnetic fields in the range of microtesla to picotesla at room temperature conditions . The RF magnetic field induces voltage in the piezoelectric material which is amplified by the microcantilever which also filters out the signal around its resonant frequency. The cantilever vibration is measured using an optical detection system or by using capacitance to impedance converter. A thick block of piezoelectric material is used as a transmitter in order to replace the transmitting coil.

Purpose: The objective of current research is to develop a miniaturised MRI system at low values of magnetic fields.

Methods: The major challenges in development of miniaturised MRIs are associated with fabrication of efficient radio transmitters and sensitive receivers at low dimensions1. Here, we present a novel design of an MRI system having a volume in the range of a couple of cm3 operating at a few hundred kilohertz with magnetic field in the range of millitesla. The receiver of the MRI system has a piezoelectric-microcantilever system having the characteristics of an integrated sensor, filter and amplifier which is difficult to achieve using conventional RF technology and can sense magnetic fields in picotesla range at room temperature conditions (Fig.1). The RF magnetic field induces voltage in the piezoelectric material which is amplified by the microcantilever which also filters out the signal around its resonant frequency. The cantilever vibration is measured using an optical detection system or by using capacitance to impedance converter. A thick block of piezoelectric material is used as a transmitter in order to replace the transmitting coil. A sample having a net magnetic moment when subjected to a static magnetic field B precesses at a certain frequency f which is given by2 where B is the magnetic field and is the gyromagnetic ratio which is expressed by , where, q is charge and m is mass of the corresponding particle. For Hydrogen atom, the value of is 42.576 MHz/Tesla which means that for a magnetic field of 1 Tesla, the frequency of radio waves would be 42.574 Tesla. The general value of static fields in present day MRIs are about 3T which sets the resonant frequency at 127.72 MHz. If we reduce the magnetic field to 1 mT, the resonant frequency would be of the order of 127.72 KHz. To detect a signal of 127 KHz, we would need an LC circuit with an inductance of at least 1.5 mH and capacitance 1 mF. The losses in a capacitor of these values are extremely high. The best way would be to use capacitances in the range of nF which would mean increasing inductances in the mH regime which would result in larger coils and higher level of Ohmic losses in the inductor. The best quality factor which we can get is 200. In order to sense the magnetic field, arrays of highly-sensitivity MEMS cantilevers mounted on piezoelectric bases as radio receivers are being tested3. The cantilevers are fabricated from doped silicon or other materials, each with a resonant frequency close to the precession frequency of the hydrogen atom in the biological sample. Such a system can pick up very low power radio signals in the range of picotesla regime and have the overall volume which is in the range of 25 mm3. The transmitting circuit comprises of a stack of piezoelectric material of dimensions 18 mmX5mmX5mm. According to the Van Dyke model, a piezoelectric material has a finite value of capacitance, inductance and resistance4. Above its resonant frequency, it behaves like an inductor. Fig 2 shows the phase changes associated with a transition from capacitive to inductive behavior of the piezoelectric stack around its resonant frequencies. The system behaves like an inductor of 0.2 mH at around 300 KHz. The corresponding inductance for a one turn coil of diameter 2 cm is 0.14 mH. The magnetic flux density generated by such a coil excited by current of 1 A at a distance of 1 cm along a square plane of 1cm3 is shown in Fig. 3. The magnetic flux density is non uniform but has a uniformity in the central region of the plane which shows a value of 6 mT. Considering the value of the inductance of the piezoelectric stack, they can easily replace such coils in order to generate similar magnetic field patterns. Thus, a complete MRI apparatus can be developed using piezoelectric stacks as transmitters, piezoelectric coupled microcantilevers as receivers and ultra-low magnetic fields (Fig.1 )

Results: A compact MEMS based radio receiver and transmitter with volume in the range of a couple of cm3 is possible using piezoelectric stack with a microcantilever mounted on it.

Discussion: These experiments show that piezoelectric-cantilever system comprising of arrays of cantilevers of different resonance frequencies can be used in place of transmitting and receiving coils of an MRI system in order to diagnose samples of low physical dimensions.

Conclusion: A MEMS based radio receiver comprising piezoelectric material with microcantilever can be used for ultra-low MRI based applications.

Acknowledgements

No acknowledgement found.

References

References:

1. Larkman, D. J., & Nunes, R. G. Parallel magnetic resonance imaging. Phys. in Med. and Boil. 2007 52(7), R15.

2. Liang, Z. P., & Lauterbur, P. C. Principles of magnetic resonance imaging. SPIE Opt. Engg. Press. 2000

3. Sinha, D., Pisana, S., & Flewitt, A. J. (2011). Radio frequency magnetic field detection using piezoelectric coupled microcantilevers. Smart Mat. and Str. 2011, 20(2), 025016.

4. Van Dyke, K. S. (1925). The electric network equivalent of a piezoelectric resonator. Phys. Rev. 1925.25(6), 895.

Figures

Fig. 1 A piezoelectric material based MRI

Fig. 2. Phase-frequency plot of a piezoelectric stack.

Fig. 3. Magnetic flux profile of a coil



Proc. Intl. Soc. Mag. Reson. Med. 24 (2016)
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