Jonathan Y Lu1, Thomas Grafendorfer2, Fraser Robb3, John M Pauly1, and Greig C Scott1
1Dept of Electrical Engineering, Stanford University, Stanford, CA, United States, 2Advanced Coils, GEHC Coils, Stanford, CA, United States, 3GE Healthcare, Aurora, OH, United States
Synopsis
We aim to demonstrate methods to wirelessly probe the MRI
transmit state without access to the internal MRI hardware itself. We
demonstrate two forms of RF pulse detection during a scan with simple magnetic
field probes: 1) an electrical link undergoing peak detection and 2) an optical
link. We process this signal as an external hardware interrupt into a microcontroller,
which can be easily used to bias a coil between receive and transmit mode. Such
a setup can be useful in future wireless receive coils.Introduction
As interest in wireless MRI increases, we questioned how to
detect the state of the MRI scanner (ie receive or transmit mode) with minimal
additional hardware components while having no access to the scanner hardware. Such
a task could eventually be used as part of a micro-controller approach to
wirelessly detune an MRI receive coil. We have seen the use of low power FET
based Q-spoiling techniques for coil detuning using Gallium Nitride FET devices
in the MRI scanner
1-2. However, we hope to complement this low power
Q-spoiling method with a means to wirelessly trigger these switches. We want to
extract information without having access to the hardware of the commercial MRI
scanner by detecting the transmit pulse externally. We do this by adding a
probe in the scanner which can relay detected RF pulses as an interrupt to a
microcontroller
3. Here, we explore two different setup links involving simple
hardware, to route the probed information to detect the state of the machine.
Materials and Methods
For a magnetic probe, we made up a small 3.5cm by 4.5cm
surface loop and tuned it to 63.88MHz, placing it 8 centimeters away from the
imaging coil so as not to affect the image. This probe was placed inside the
scanner and was unconnected to any scanner hardware, making it wireless from
the system. In our first setup, we routed this probe signal using a coaxial
cable leading to a LTC 5536 peak detector, which would then trigger an
interrupt on a microcontroller in the console room (Fig 1a, 2). In our second
setup, we instead routed this probe signal optically using an IE-E97 LED and a
photo-logic detector IF-D96F in order to trigger the interrupt instead (Fig 1b,
3).
As a proxy for the RF transmit mode detection, the
microcontroller will switch on an LED to visually indicate RF pulse detection
during the scanner transmit mode. This digital logic can easily be attached to
the gate of a FET switch, for example, to activate Q-spoiling or to trigger a
readout.
We used an Arduino Mega 2560 microcontroller board, which is
centered on the ATmega2560 8-bit microcontroller with an AVR-based architecture.
We ran both an SPGR gradient echo sequence (GRE) (TE=25ms, TR=50ms, flip
angle=60°,
resolution=1.04mmx1.04mm) and a fast spin echo pulse (FSE) (TE=20ms, TR=500ms,
echo train=4, resolution=1.04mmx1.04mm) on a General Electric 1.5T scanner.
Results and Discussions
Both our peak detector setup, and our optical link setup
functioned properly, and we were able to successfully observe an LED flashing
in sync with the scanner in transmit mode. Both setups, involving the peak
detector or optical link, were connected by a 5V supply at the receive end of
the probe. On the microcontroller, we
had to set up the necessary registers (EIMSK and EICRB in the AVR architecture)
so that the microcontroller will detect external hardware interrupt of either a
rising edge or a falling edge (Fig 4 for code snippet).
We can visualize from the LED indicator attached to the
microcontroller, that the probe was successfully reading the transmit signals
and relaying it to the Arduino. (Fig 5 animation). Both methods implemented
were successful. One caveat we had to take into account was the induced EMF. Using
our sniffer loop area, and assuming 0.2 G maximum RF strength, we calculated
the induced EMF to be 12.6V. Our loop has only 2 capacitors on each side, resulting
in ~6.3V across each of the capacitors. Therefore, we made sure that the
LTC5536 peak detector and the IE-E97 LED can handle input voltages of ~6.3V.
From the datasheet, the IE-E97 LED had a maximum reverse
breakdown voltage of~6V and so we added in an antiparallel protection diode. In
fact, when we removed the protection diode from the circuit to rerun a fast spin echo sequence, the LED was damaged after the scan, further validating our
suspicions.
Conclusions
We successfully demonstrated two means of RF transmit peak
detection while having limited access to the scanner hardware. This can
potentially be useful as a quick and easy way to activate and deactivate the
readout of auxiliary electronics in the bore, or even actively spoiled MRI
receive coils. Interestingly, θ,-θ
pulses (0 degree NOOP) would trigger low-data bit rates for setting microcontroller
states under pulse sequence control. These approaches may provide useful tools
for prototyping wireless MRI systems.
Acknowledgements
Stanford Graduate Fellowship, National
Science Foundation, NIH Grant R01EB019241, R01EB008108, P01CA15999, GE
Healthcare research supportReferences
1.
Twieg M, et al., "Enhancement Mode GaN on Silicon (eGaN FETs) for Coil Detuning",
Proc Intl Soc Mag Reson Med. #0926, 2014
2.
Lu J, et al., "Q-spoiling method using depletion mode Gallium Nitride (GaN) HEMT
devices at 1.5T", Proc Intl Soc Mag Reson Med. #2150, 2015
3. Atmel, "Atmel AT mega640/V-1280/V-1281/V-2560/V-2561/V", 8-bit Atmel Microcontroller datasheet, 2014