Nao Kodama1 and Katsumi Kose1
1Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan
Synopsis
Echo planar imaging sequences were developed for a 9.4 Tesla vertical standard bore (~54 mm) superconducting magnet using an unshielded gradient coil. Because EPI requires fast switching of intense magnetic field gradients, eddy currents were induced in the surrounding metallic materials, e.g., the room temperature bore, and this produced serious artifacts on the EPI images. We solved the problem using an unshielded gradient coil set of proper size (39 mm OD, 32 mm ID) and reference scans. The obtained EPI images of a phantom and a plant sample were almost artifact free and demonstrated the promise of our approach.Introduction
High-field vertical standard (54 mm) bore
superconducting magnets are widely used for NMR spectrometers. These magnets
are very useful to MRI studies because the homogeneity and stability of the
magnetic fields are excellent. However, their room temperature bore are usually
made of Cu and eddy currents produced by the gradient field switching cause
serious artifacts on the MR images. In particular, because echo-planar imaging
requires intense readout gradients, solution of the eddy current problem is
essential. We solved the problem using a proper size unshielded gradient coil
set and reference scans, and succeeded in installing several EPI sequences for
a 9.4 T superconducting magnet.
Materials and Methods
We
developed an MRI system using a 9.4 Tesla vertical standard bore
superconducting magnet (JASTEC, Kobe, Japan), a home-built room temperature second-order
shim coil set (50 mm o.d. and 40 mm i.d.), an unshielded gradient coil set (39
mm o.d. and 32 mm i.d.), and an eight-rung birdcage coil (19.5 mm o.d.) tuned
to 400.4 MHz. The gradient coil elements were made from Cu rods as
follows: coil patterns designed with the target field method were cut on the
surface of the rods using a five-axis numerically controlled lathe; the
trenches made by the lathe were filled with epoxy resin, and were finally bored
to cylindrical shapes with 0.8 mm thickness. Three cylindrical gradient
elements were assembled to a rigid gradient coil set using a vacuum
impregnation technique. Figure 1 shows its picture, specifications, and eddy
current properties measured in the magnet bore. A digital MRI transceiver
(DTRX6, MRTechnology, Tsukuba, Japan) controlled by a PC controller was used
for generation of pulse sequences [1].
One shot 2D EPI sequences with 1ms readout-gradient
switching intervals, 64 ms signal readout time, and 80 ms spin-echo time were
developed for a 15.36 mm square FOV (2 mm slice-thickness) with a 64 × 64 image matrix. Multishot 2D and
3D EPI sequences with 128 × 128, 256 × 256, and 256 × 256 ×
16 image matrices were developed for a 15.36 mm square FOV (2 mm slice-thickness)
and a 15.36 mm cube FOV. Before the EPI image acquisitions, the reference scans
that phase encoding gradients were switched off were acquired to measure the
peak positions and phases of the multiple gradient echo peaks. A water phantom
consisting of 19 glass capillaries in a test tube (10 mm o.d and 9 mm i.d.) and
a stem of celery were used for image evaluation.
Results
Figure
2 shows peak positions of the multiple gradient echoes in the switching
intervals, phases of the gradient echo peaks, and differences of successive
phases of the gradient echo peaks in the reference scans of the one-shot EPI
sequences with Gx and Gy readout-gradients. These results were used to correct the
positions along the readout gradients (resampling) and phases of the echoes.
Figure 3 shows reconstructed EPI images with no correction, after resampling,
and after both resampling and phase correction with Gx and Gy readout
gradients. Figure 4 shows multishot EPI images with 128 × 128 and 256 × 256 pixels. The profiles of the
enlarged images clearly demonstrated the spatial resolution of 120 and 60 mm. Figures 5(a) and (b) show 256 × 256 ×
16 pixel 3D EPI images of the water phantom and a stem of celery. Slices near
the central regions had no artifact but ghosting artifacts were observed for
the slices near the edges.
Discussion
Figure
1 clearly shows that time constants of the eddy currents induced by the
gradient switching are categorized into two groups; ~0.3 and ~2 ms. Because the
readout gradient switching intervals were 1 ms, the eddy gradient fields with
~0.3 ms time constants affect the rise of the readout gradients but the effects
stayed within the readout interval. In contrast, the eddy gradient fields with
~2 ms time constants affected later several echoes, which were observed as the
decaying oscillation of the peak positions shown in Figs.2(a) and (d). The
discontinuous change of the phases of the echo peaks are B0 shifts
induced by the switching of the readout gradients. Although the EPI signals
acquired in the magnet were affected by the eddy currents induced by the
intense readout gradients, the effects were successfully corrected by the reference
scan as shown in Figs.3-5. We therefore concluded that EPI was successfully
installed in the standard and Cu bore vertical magnet using a proper size
unshielded gradient coil set and the reference scans.
Acknowledgements
This work was so supported by Japan Science and Technology Agency (Haishi project).References
[1]
S. Hashimoto, K. Kose, T. Haishi, Rev. Sci. Instrum. 83, 053702 (2012).