MR imaging is limited by poor evaluation of lung parenchyma due to rapid single decay, low tissue portion density and substantial respiratory motion. In this study, we evaluate three different approaches of VIBE sequences in pulmonary lesions detection, which including a short-TE breath-hold VIBE, DIXON VIBE and a free-breathing Radial VIBE.This study was approved by the local ethics committee, and all patients gave written informed consent. 56 patients (42 male and 14 female; mean age, 65.5±9.37; age range, 48-81) with 22 of non-small cell lung cancer (NSCLC), 10 of small cell lung cancer (SCLC)，14 of metastatic tumors, and 10 of benign were recruited in this study. All MR imaging was performed on a 1.5 T MR scanner (MAGNETOM Aera, Siemens AG, Erlangen, Germany). Three VIBE sequences with slice thickness of 3 mm, matrix of 384×288 and FOV of 400×262 mm2 were performed for each patients: 1) breath-hold short-TE VIBE with TR/TE = 4.02/1.91 ms, flip angle = 5 degree, CAIPIRINHA = 2×2, TA = 19 s; 2) breath-hold Dixon VIBE with TR/TE1/TE2 = 6.75/2.4/4.8 ms, flip angle = 10 degree, CAIPIRINHA = 2×2, TA = 15s; 3) free-breathing Radial VIBE with TR/TE = 3.84/1.91 ms, flip angle = 12 degree, TA = 212 s. All images were assessed by two radiologists with 5 and 20 years of experience. The numbers of lesions were counted for different groups categorized by the short-axis diameter of less than 10 mm, and larger than10 mm.A total of 88 lesions were detected by CT, with 28 of a diameter less than 10 mm and 60 of a diameter lager than 10 mm. For 28 lesions with a diameter less than 10 mm, all were detected by short-TE VIBE and Dixon VIBE, and 20 were detected by Radial VIBE; and for 60 lesions with a diameter larger than 10 mm, all were detected by short-TE VIBE and Dixon VIBE, and 56 by Radial VIBE.Lung cancer is the most frequently diagnosed cancer with one of the highest mortality rates. In this study, we compared three VIBE sequences in detection of the pulmonary lesions in patients with lung cancer, and found the breath-hold short-TE VIBE and breath-hold Dixon VIBE sequences have the similar lesion detection rate. However, the delineation of tumor boundary was clear in short-TE VIBE. Radial VIBE sequence is useful for free-breathing examination in patients of young age and pathologies with difficulties to hold breath during MR examination, but it has lower lesion detection rate than the breath-hold VIBE sequences. breath-hold short-TE VIBE and Dixon VIBE sequences have better performance in lesion detection than radial VIBE.