Flow-Related Artifacts and Pitfalls in Magnetic Resonance Imaging/Angiography in Neuroradiology
Jae W Song1

1Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States

Synopsis

Artifacts related to flow are common and can be a diagnostic pitfall for the interpreting neuroradiologist, if it is not recognized accurately. It is critical for the interpreting neuroradiologist to have a fundamental understanding of the physics that underlie image formation and the types of artifacts that emerge from magnetic resonance imaging and angiography. We present a pictorial essay of commonly encountered flow-related artifacts and pitfalls in magnetic resonance imaging and angiography in neuroradiology and discuss the physics behind the formation of the artifact as well as how to minimize the artifact. Knowledge of these artifacts and pitfalls is essential to arrive at accurate diagnoses.

Purpose

It is critical to recognize magnetic resonance (MR) imaging and angiography (MRA) artifacts related to flow in neuroradiology. Artifacts can be mistaken for pathology or obscure underlying anatomy, which can result in misdiagnosis. The purpose of this educational exhibit is to discuss commonly seen flow-related MR imaging and angiography artifacts and pitfalls in neuroradiology by providing imaging examples, describing the physics of the formation of the artifacts, and discussing how to correct the artifacts or minimize them.

Outline of content

Imaging flow is unique and complex. Unique properties of flowing blood include the inflow effect of nonsaturated flowing blood, outflow effect of excited flowing blood, and the susceptibility of blood to dephasing from complex or turbulent blood flow. Unawareness that these properties can result in the presence or absence of signal can result in misinterpretation and be a pitfall for stenosis, thrombus, or vessel spasm.

Here we discuss pitfalls and artifacts related to flow that are commonly encountered in neuroradiology in the following four categories.

(1) Motion artifact

a. Pulsation artifact in vessels (FIGURE 1) and CSF-related in the phase-encoding direction

(2) Flow related artifact

a. Flow-reversal artifact (FIGURE 2)

b. In-plane saturation artifact

c. Slow flow artifact

d. Entry section phenomenon (FIGURE 3)

(3) Magnetic field inhomogeneity

a. Susceptibility artifact from metal (FIGURE 4)

b. Pseudostenosis artifact related to susceptibility from residual contrast in vein

(4) Post-processing related to reconstruction of maximum intensity projection

a. Stair-step artifact (FIGURE 5)

b. Venetian blind artifact

c. Shine-through artifact

For each type of artifact, the physics behind the artifact and how to correct or minimize the artifact as well as how some artifacts have clinical utility to help diagnose pathology will be discussed.

Summary

Radiologists should be familiar with most common MRI and MRA artifacts and recognize them to accurately diagnose pathology. Understanding the mechanism and appearance of flow-related artifacts is essential for accurate image interpretation in neuroradiology.

Acknowledgements

No acknowledgement found.

References

1. Morelli JN, Runge VM, Ai F, Attenberger U, Vu L, Schmeets SH, Nitz WR, Kirsch J. An Image-based Approach to Understanding the Physics of MR Artifacts. Radiographics. 2011;31:849-866.

2. Kaufman JA, McCarter D, Geller SC, Waltman AC. Two dimensional time-of-flight MR angiography of the lower extremities: artifacts and pitfalls. AJR Am J Roentgenol 1998; 171:129-135.

3. Zhang, Maki. 3D contrast-enhanced MR angiography. J Magn Reson Imaging. 2007;25(1):13-25.

Figures

(A) A basilar tip aneurysm (red arrow) identified on this axial T1-weighted spin echo sequence demonstrates pulsation artifact. Periodic pulsations result in ghosting artifact in constant intervals in the phase-encoding direction (red arrows). (B) The presence of an aneurysm is confirmed on a CTA 3D reformatted image (red arrow).

(A) In a 2D Time-of-flight (TOF) image, the left vertebral artery is not visualized (yellow arrow) due to signal suppression from retrograde flow from a (B) high-grade stenosis of the left subclavian artery (red arrow) seen on a contrast enhanced 3D MRA with complete opacification of the left vertebral artery confirming patency (yellow arrow).

(A) Sagittal and (B) axial T1-weighted GRE images of the brain reveal increased signal in the vessels and skullbase due to entry section phenomenon, which is due to new protons entering the image during acquisition. Awareness of this artifact is critical to avoid interpreting this signal as a thrombus.

(A-C) An ovoid signal void (red arrows) in the region of the right middle cerebral artery is present from susceptibility artifact, due to magnetic field distortion from a surgical clip (D). The metallic object results in distortion of the magnetic gradient with accelerated dephasing of spins and signal loss.

(A-B) Stair step artifact is the pixelated appearance of obliquely oriented vessels on 2D TOF MIP images and is due to thicker 2D slices than the actual in-plane spatial resolution. This artifact can be minimized by increasing slice overlap but at the expense of increasing scan time and slice number.



Proc. Intl. Soc. Mag. Reson. Med. 24 (2016)
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