Synopsis
The
aim of this study was to determine the value of combining conventional MR
imaging (MRI), diffusion-weighted (DW-MRI) and dynamic contrast enhanced MRI
(DCE-MRI) in diagnosing solid neoplasms in the parotid gland.
Materials and Methods：A total of 148 subjects (101 with benign
and 47 with malignant tumors) were evaluated with conventional MRI, DW-MRI and
DCE-MRI prior to surgery and pathologic verification. The items observed with
conventional MRI included the shape, capsule and signal intensity of parotid
masses. The apparent diffusion coefficient (ADC) was calculated from DW-MRI that was obtained with a b factor of 0 and
1000 s/mm2. A time-intensity curve (TIC) was
obtained from DCE-MRI.
Results：There were significant differences
(p<0.01) in the shape, capsule, ADC and TIC between benign and malignant
parotid tumors. Irregular neoplasms without capsule, ADC < 1.12×10-3mm2/s, and a plateau enhancement pattern
were valuable parameters for predicting malignant neoplasms. A combination of all
of these parameters yielded sensitivity, specificity, accuracy, and positive
and negative predictive values of 85.1%, 94.1%, 91.2%, and 87.0% and 93.1%,
respectively.
Conclusion：A combined
analysis using conventional MRI, DW-MRI and DCE-MRI is helpful to distinguish
benign from malignant tumors in the parotid gland. Purpose
Purpose：The aim of this study was to determine
the value of combining conventional MR imaging (MRI), diffusion-weighted (DW-MRI)
and dynamic contrast enhanced MRI (DCE-MRI) in diagnosing solid neoplasms in
the parotid gland.
Materials and Methods
Materials and Methods：A total of 148 subjects (101 with benign
and 47 with malignant tumors) were evaluated with conventional MRI, DW-MRI and
DCE-MRI prior to surgery and pathologic verification. The items observed with
conventional MRI included the shape, capsule and signal intensity of parotid
masses. The apparent diffusion
coefficient (ADC) was calculated from DW-MRI that was obtained with a b factor
of 0 and 1000 s/mm2. A time-intensity curve (TIC) was
obtained from DCE-MRI.
Results
Results：There were significant differences
(p<0.01) in the shape, capsule, ADC and TIC between benign and malignant
parotid tumors. Irregular neoplasms without capsule, ADC < 1.12×10-3mm2/s, and a plateau enhancement pattern
were valuable parameters for predicting malignant neoplasms. A combination of all
of these parameters yielded sensitivity, specificity, accuracy, and positive
and negative predictive values of 85.1%, 94.1%, 91.2%, and 87.0% and 93.1%,
respectively.
Conclusion
Conclusion：A combined
analysis using conventional MRI, DW-MRI and DCE-MRI is helpful to distinguish
benign from malignant tumors in the parotid gland.
Acknowledgements
No acknowledgement found.References
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