Craig H. Meyer1, Samuel W Fielden1, Josef Pfeuffer2, John P. Mugler III3, Alto Stemmer2, and Berthold Kiefer2
1Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 3Department of Radiology & Medical Imaging, University of Virginia, Charlottesville, VA, United States
Synopsis
The purpose of this
work was to apply a spiral k-space characterization method to a variety of
scanner models to assess the consistency of characterization parameters and the
ability of the method to yield high-quality spiral images on the different
scanners. Characterization of
gradient-system performance on 11 MR scanners yielded only minor variation in
parameter values among scanners, and in all cases model-based correction of
spiral trajectories yielded very similar image results to reconstruction based
on measured trajectories. These results
suggest that model-based reconstruction may represent a viable approach for
obtaining high-quality spiral images without the need for characterization of
specific spiral-trajectory implementations. Introduction &
Purpose
Spiral k-space trajectories have been
investigated by many researchers as a more efficient alternative to widely-used
rectilinear (Cartesian) trajectories, offering advantages in terms of acquisition
speed, reduced sensitivity to motion and shorter minimum echo times [1]. Nonetheless, despite many research studies
demonstrating promising results, spiral trajectories have yet to become
available among the standard techniques offered on commercial MR scanners. In this regard, a practical limitation is
that, compared to Cartesian trajectories, the quality of imaging results for
spiral trajectories is much more dependent on gradient-system fidelity. This limitation has often been addressed by
measuring the actual (vs. theoretical) k-space
trajectory of a specific implementation (i.e., selected orientation, FOV, etc.)
for use in image reconstruction; however, this approach is impractical for
widespread application of spiral imaging.
Tan and Meyer [2] proposed a method of characterizing scanner performance
for spiral trajectories, which can be used to perform a model-based correction at
image reconstruction, applicable to freely chosen imaging parameters. The purpose of this work was to apply this
characterization method to a variety of scanner models to assess, across
scanners, the consistency of characterization parameters and the ability of the
method to yield high-quality spiral images on the different scanners.
Methods
The scanner
characterization procedure was based on 15 image datasets (5 from each of the
primary axes) acquired from a spherical phantom using a prototype pulse sequence
(total acquisition time < 8 min).
These were processed with a MATLAB script to yield, in addition to
measured k-space trajectories,
gradient delays and eddy-current terms for each axis that can be incorporated
into reconstruction for trajectory correction [2]. This procedure was applied to 11 scanners,
including 1.5T scanners (MAGNETOM Dot Avanto, Siemens Healthcare; MAGNETOM Aera,
Siemens Healthcare) and 3T scanners (MAGNETOM Skyra, Siemens Healthcare; MAGNETOM
Prisma, Siemens Healthcare), and 2 software levels. To assess the degree to
which image quality was improved by incorporating model-based trajectory
correction into the reconstruction, the root mean squared error (RMSE) was
calculated for images reconstructed based on measured k-space trajectories (gold standard) compared to those
reconstructed using theoretical trajectories corrected for nominal isotropic gradient
delays, for anisotropic gradient delays from system characterization, and for anisotropic
gradient delays plus eddy-current terms from system characterization.
Results
Across all
scanners, the variation (standard deviation) of the gradient delays along the
three physical axes ranged from 0.3 to 0.9 ms. Some of this variation
would be expected to arise from the different models of gradient systems among
scanners. For example, considering only seven
3T scanners, the variation of gradient delays was smaller, ranging from 0.1 to
0.4 ms. The eddy-current terms were relatively small
among all scanners (reflecting that the baseline eddy-current compensation
performed well for the spiral waveforms), although there were systematic
differences among scanner models.
Considering again the seven 3T scanners, the maximum coefficient of
variance for eddy-current terms was less than 10% and the mean was 7%. Comparing model-based reconstruction to reconstruction
using measured trajectories, anisotropic gradient delays alone provided an
average reduction of 3.4% in RMSE relative to nominal isotropic delays, and
anisotropic gradient delays plus eddy current terms provided an average
reduction of 37.3% in RMSE. Thus, the
gradient delays on these systems were relatively isotropic.
Visually,
it was difficult to discern differences between spiral images reconstructed
using measured trajectories and those reconstructed using model-based
parameters including gradient delays and eddy-current terms for each axis. Representative images are shown comparing transverse
(Fig. 1), coronal (Fig. 2) and sagittal (Fig. 3) images from measured
trajectories to the corresponding images from model-based trajectory correction. The difference images illustrate the small
remaining error between the two image sets.
The eddy-current terms corrected image scaling errors resulting from
variations in the magnitude of the gradient transfer function as a function of
gradient temporal frequency [3]. Spiral abdominal images of a volunteer are shown in Fig. 4.
Conclusions
Characterization
of gradient-system performance on 11 MR scanners yielded only minor variation
in parameter values among scanners, and in all cases model-based correction of
spiral trajectories yielded very similar image results to reconstruction based
on measured trajectories. The calibration results for a particular scanner were
stable over time, and the calibration results were similar for this group of scanners. These results suggest that
model-based reconstruction may represent a viable approach for obtaining
high-quality spiral images without the need for characterization of specific spiral-trajectory
implementations. Nonetheless, future
work is needed to verify the approach on additional MR scanners, and for a wide
variety of spiral-trajectory implementations (orientation, FOV, spatial
resolution, number of interleaves, etc.).
Acknowledgements
No acknowledgement found.References
1. Meyer CH et al. Magn Reson Med 1992; 28:202-213.
2. Tan H, Meyer CH.
Magn Reson Med 2009; 61:1396-1404.
3. Addy NO, Wu HH,
Nishimura DG. Magn Reson Med 2012; 68:120-9.