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Diffusion Weighted Imaging Detects Significant Cohort Responses After Seven Days of Treatment with Cediranib in a Phase I Clinical Trial Setting

Author:Matthew R. Orton  Christina Messiou  David John Collins  Veronica A. Morgan  Dionysis Papadatospastos  Andre Brunetto  Jooern Ang  Helen Mann  Jean Tessier  Helen Young  Stan Kaye  Johann S. de Bono  Martin O. Leach  Nandita M. De Souza  

Session:Tumor Therapy Response: Clinical & Preclinical  

PCA of Combined DCE-MRI Data from a Large Cohort Can Be Used to Assess Treatment Effects with Similar Sensitivity to Pharmacokinetic Model Fitting

Author:Matt Nathan Gwilliam  David John Collins  Martin O. Leach  Helen Young  Matthew R. Orton  

Session:Perfusion & Permeability  

Significant Increases in Contrast Arrival Time Measured with DCE-MRI Are Seen After Treatment with an Anti-VEGF Agent

Author:Matthew R. Orton  Matthew Gwilliam  Christina Messiou  David John Collins  Veronica A. Morgan  Helen Young  Nandita M. De Souza  Martin O. Leach  

Session:Cancer of Breast & Body