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Pre-Clinical Assessment of Anti-Vascular Effects of Novel Combretastatin A-4 Analogues by Dynamic Contrast Enhanced MRI

Relative Changes in Tumor Perfusion (Ktrans, Ve) is Independent of Absolute Baseline T1 Values

Using Dynamic Contrast Enhanced MRI and Immunohistochemistry to Monitor Tumour Response to Tirapazamine, a Hypoxia-Targeting Chemotherapeutic Agent