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Alcoholic patients that remain abstinent for more than 3 months show larger spectroscopic and morphologic abnormalities than relapsing patients at the beginning of withdrawal

Deformation-Based-Morphometry shows widespread reversible atrophy in detoxifying alcoholics

Rise in frontal white matter choline is correlated with reversing atrophy in detoxifying alcoholic patients

Time line follow back of alcohol consumption is positively correlated with brain choline levels in healthy volunteers