Alexey V. Dimov1, Nanyque A. Boyd2, Keigo Kawaji2,3, and Timothy J. Carroll1
1Radiology, University of Chicago, Chicago, IL, United States, 2Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, United States, 3Medicine, University of Chicago, Chicago, IL, United States
Synopsis
Rosette
k-space sampling is an attractive tool for a variety of applications such
QSM, DCE, etc.
However, as many non-Cartesian
acquisition schemes, rosette is highly susceptible to the system-specific gradient delays. We present a robust
technique utilizing intrinsic symmetries of multi-shot rosettes, which allows to
reconstruct images with minimal artifacts due to misalignment of the k-space points.
Target audience
Researchers interested in non-cartesian MRIPurpose
The Rosette k-space sampling [1] (Fig. 1) is an attractive approach for a variety of applications such Quantitative Susceptibility Mapping (QSM), Dynamic Contrast Enhanced MRI, as well as any $$$R_2$$$ or $$$R_2^*$$$ mapping approaches. However, the Rosette sampling is highly susceptible to the system-specific gradient delays, off-resonance, and resultant trajectory errors [2]. While iterative correction approach can be employed with the joint estimation of magnitude, phase, and $$$R_2^*$$$, such approaches are potentially time-consuming. In this work, we present a robust technique that utilizes intrinsic rotational symmetries of a multi-shot Rosette pulse sequence design, which can thereby allow reconstruction of images with reduced artifacts caused by the misalignment of the sampled points along the measured trajectory.Methods
The proposed method utilizes intrinsic symmetries in multi-shot multi-echo rosette with even number of acquired arms. In particular, for any $$$i<N/2$$$, arms $$$i$$$ and $$$i+N/2$$$ are traversing the center of the k-space in the opposite directions and in tangential manner (Fig 2). Under ideal conditions, values measured along the rosette spokes belonging to these arms should be aligned in the k-space center. If, however, imperfect gradient timing is present, spokes’ phase and magnitude profiles will differ by a noticeable shift $$$\delta$$$ (Fig 3). This shift can be estimated through a cross-correlation of analysis of the tangential spokes and eliminated prior gridding.The algorithm of the proposed correction method can be summarized as follows:
- Split $$$N$$$ arms into $$$N/2$$$ arm pairs
- For each resulting pair of spokes $$$\{S_1, S_2\}$$$, calculate correlation $$$c = FT\{|S_1|\}\cdot FT\{|\tilde{S_2}|\}^*$$$. Here "~" denotes inversion ("flip") of the spoke points, and $$$FT\{\}$$$ is Fourier transform.
- Estimate slope $$$\alpha$$$ in the phase of $$$c$$$
- Shift each of the spokes by $$$\frac{L\alpha}{4\pi}$$$
Experimental validation
2D multi-shot rosette sequence was implemented on a 3T MR platform (Philips Achieva). A phantom dataset was acquired using a 64-arm rosette sequence (FOV = 22 cm, Slice thickness = 5 mm, # Slices = 1, TR = 24-30 ms, TE = 0.8-1.2ms, 24 echoes). No parallel imaging was used. A volunteer data was additionally acquired using similar scan parameters.The gridding reconstruction, implemented offline using MATLAB (The Mathworks, Natick, MA) with CUDA-PTX graphical processing unit acceleration (NVIDIA, Santa Clara, CA) of the original data and data corrected using the proposed technique was performed. Image magnitude, phase, and presence of off-resonance artifacts was examined using region-of-interest analysis.
Results
Figure 4shows the images reconstructed by both methods from the phantom data, and results of field inhomogeneity estimation based on 20 consecutive rosette echoes. The proposed correlation-based method successfully eliminated artificial intensity modulation present in the magnitude, as well as fringe lines in the phase of the gridded images. Phase of individual echo images demonstrates linear behavior which allows for estimation of a high-quality field map. Processed volunteer data demonstrates similar level of quality in resulting images.Inspection of the post-correction k-space (Fig 5) showed accurate alignment of the k-space profiles of different rosette arms.Discussion and conclusions
We demonstrate the feasibility of a simple algorithm for retrospective correction of system-dependent gradient delays that does not require additional data acquisition. The proposed method demonstrated reliable performance and allowed artifact-free reconstruction of multiple consecutive multi-shot rosette echoes, making rosette applicable for fast mapping of the inhomogeneity field. The method can be easily generalized to the cases of rosettes with odd number of arms, as well as other self-intersecting trajectories (e.g., radial), and EPI. Acknowledgements
No acknowledgement found.References
- Noll DC, et.al., Magn Reson Med. 1998 May;39(5):709-16
- Peters DC, et al., Magn Reson Med. 2003 Jul;50(1):1-6.