Hybrid radiation therapy and magnetic resonance imaging (MRI) systems are providing new options for cancer therapy. In our design the B0 rotates on a gantry along with the linear accelerator (linac) for treatment delivery. This introduces new challenges to RF-coil design as the plane of MR precession changes depending on gantry angle. Our three channel array is appropriate for the head and consists of two butterfly coils and a circular loop. The array provides equal SNR at all gantry angles while allowing a radiation window to avoid collisions between the radiation beam and the RF-coils.
In our rotating-field scanner, RF coils must be sensitive to magnetization along all three perpendicular axes for optimal and constant sensitivity at all gantry angles. The three-channel receive-only head array, includes a circular loop that couples to the patient axis which is ⊥ to B0 at all times. Two butterfly coils3 couple to the horizontal and vertical axes perpendicular to the patient axis (Fig. 2). The circular loop is a copper ring (3.2 mm wide, 24 cm ⌀) with tuning provided by three capacitors distributed in series (2x 82 pF, 1x 75 pF). Each butterfly coil consists of two D’s (24 cm ⌀) of copper tape (5 mm wide) connected with straight copper wire (1.4 mm ⌀) and the butterfly mode is tuned to the Larmor frequency (20.56 MHz) with capacitors (150 pF and 60 pF in parallel) as shown in Figure 3. Each coil is matched to 50 Ω and includes passive detuning networks consisting of toroidal inductors (380 nH) and crossed-diodes (1N4148 diodes) in parallel with the tuning capacitors.
Bench measurements of quality factor (Q), matching and isolation were performed on a Rohde and Schwarz ZVL3 VNA using low (-15 dBm) output power to avoid activating the passive traps.The three channels were each connected to a MAR 8+ preamplifier (Mini Circuits), providing 31 dB gain and a 3 dB noise figure. Bench measurements and imaging were performed using a 2-litre aqueous cylindrical phantom (11.5 cm in diameter and 21 cm in length), containing 55 mM NaCl and 5 mM NiCl2.
Gradient echo images (single slice, 5 mm thick, 35 cm FOV, flip angle 80 deg, TE 12 ms, TR 140 ms) and noise scans were acquired with B0 at 0° (vertical), 45°, and 90° (horizontal) with the phantom positioned at the isocenter (Fig. 2). The circular loop was positioned 18 cm from the two butterfly coils. This 18 cm gap represents the maximum window required for a treatment beam for the head. The iso-center along the patient axis was 8 cm from the butterfly arrays and 10 cm from the circular loop as the circular loop is expected to have greater penetration. At each angle one axial slice (parallel to B0 and perpendicular to patient couch) and one coronal slice (parallel to couch) were acquired and the raw data for each channel was saved and reconstructed individually in MATLAB. For each angle and slice the individual images were combined into a single SNR image with weighted root sum of squares (wRSS) combination4. SNR for each channel was evaluated as the ratio of the mean signal in a 4.5⨉8.5 cm2 ROI at the center of the phantom and the standard deviation of the noise image.
We thank Paramed for technical support and Emmanuel Blosser and Cory Lambert for expertise with the Linac-MR. Mechanical components were built by Lance Spiridon and Curtis Osinchuk. We also thank Dr. Satyapal Rathee and Dr. Andrei Ghila for discussions on the collision of the radiation beam and RF-coils.
We acknowledge funding from Natural Sciences and Engineering Research Council (NSERC), Alberta Cancer Foundation (ACF), and Alberta Innovates Health Solutions (AIHS). Special thanks to Alberta Health Services (AHS) for their continued support of the Alberta Linac-MR project.