Wei Xia1,2, Xi Zhu1,2, and Weiqiang Dou3
1Subei Peoples Hospital of Jiangsu Province, Jiang Su Yang Zhou, China, 2Subei Peoples Hospital of Jiangsu Province, YangZhou, China, 3GE Healthcare, MR Research, Beijing, China
Synopsis
Although the data for the objective image quality of silent MR do not correspond with the subjective image quality scores, these data can greatly improve the success rate of the examination, reduce acoustic noise, improve patient comfort, and allow for higher overall diagnostic usefulness when compared with those of conventional MR. In summary, silent MR is more suitable for the infant brain than conventional MR.
Objective
The main goal of this study was to evaluate the application value of Silent MR in infant brain measurement.
Materials and Methods
All MRI experiments were implemented on a 3T MR system (Discovery 750w, GE Healthcare, USA).
A retrospective study of 834 cases of infants with brain MRI (440 males, 394 females, age 3 days to 36 months old, median age 18 months old, mean age 12.6 ± 3.1 months old) was performed, of which 391 cases in the conventional group, and 443 cases in the silent group. The success rate of the two groups was compared. The acoustic noise of each sequence was measured and 30 normal hearing volunteers were randomly selected to subjectively score the acoustic noise of each sequence. The signal-to-noise-ratio (SNR) and contrast-to-noise-ratio (CNR) of diffusion weighted imaging (DWI), T2 weighted and T1 weighted MRI sequences of each group were analyzed and the subjective image quality scores were obtained by using lesion visibility, lesion delineation, gray–white differentiation and overall diagnostic usefulness as the indicators. The difference was statistically significant at P < 0.05.
Results
The success rate of Silent MR was 9.5% higher than that of conventional MR. The acoustic noise of all silent sequences was lower than the conventional sequence, and the results were consistent with the subjective acoustic noise score (P<0.05). Silent sequences vs sequences provided decreased SNR, but increased CNR (P<0.05). The lesion delineation of all silent sequences was not statistically significant compared with the conventional sequences. Lesion visibility and gray–white differentiation of all silent sequences were higher than the conventional sequence (P<0.05). The overall diagnostic usefulness of the silent group was higher than that of the conventional group (P<0.05).
Conclusion
Although some objective image data and subjective image scoring results are not uniform, Silent MR can effectively improve the success rate of examination, reduce noise and increase patients’ comfort, and the overall diagnostic usefulness is higher compared with conventional MR. In conclusion, we believe that Silent MR is more suitable for infant brain than conventional MR.
Acknowledgements
I would like to express my gratitude to all those who helped me during the writing of this thesis.My deepest gratitude goes first and foremost to Professor Luo Xianfu, my supervisor, for his constant encouragement and guidance. He has walked me through all the stages of the writing of this thesis. Without his consistent and illuminating instruction, this thesis could not have reached its present form. Second, I would like to express my heartfelt gratitude to Professor Ye Jing, who led me into the world of translation. I am also greatly indebted to the professors and teachers at the Department of English,who have instructed and helped me a lot in the past two years. Last my thanks would go to my beloved family for their loving considerations and great confidence in me all through these years. I also owe my sincere gratitude to my friends and my fellow classmates who gave me their help and time in listening to me and helping me work out my problems during the difficult course of the thesis.References
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